Detalles de la búsqueda
1.
Brivaracetam, a selective high-affinity synaptic vesicle protein 2A (SV2A) ligand with preclinical evidence of high brain permeability and fast onset of action.
Epilepsia
; 57(2): 201-9, 2016 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-26663401
2.
Cross-Species Differences in the Preclinical Pharmacokinetics of CT7758, an α4ß1/α4ß7 Integrin Antagonist.
Drug Metab Dispos
; 43(9): 1381-91, 2015 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-26153275
3.
Anti-ictogenic and antiepileptogenic properties of brivaracetam in mature and immature rats.
Epilepsia
; 56(5): 800-5, 2015 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-25818358
4.
A biomarker assay validation approach tailored to the context of use and bioanalytical platform.
Bioanalysis
; 15(13): 757-771, 2023 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-37526064
5.
2021 White Paper on Recent Issues in Bioanalysis: Mass Spec of Proteins, Extracellular Vesicles, CRISPR, Chiral Assays, Oligos; Nanomedicines Bioanalysis; ICH M10 Section 7.1; Non-Liquid & Rare Matrices; Regulatory Inputs (Part 1A - Recommendations on Endogenous Compounds, Small Molecules, Complex Methods, Regulated Mass Spec of Large Molecules, Small Molecule, PoC & Part 1B - Regulatory Agencies' Inputs on Bioanalysis, Biomarkers, Immunogenicity, Gene & Cell Therapy and Vaccine).
Bioanalysis
; 14(9): 505-580, 2022 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-35578993
6.
Pharmacokinetic interaction of brivaracetam on other antiepileptic drugs in adults with focal seizures: Pooled analysis of data from randomized clinical trials.
Epilepsy Res
; 158: 106218, 2019 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31675621
7.
European Bioanalysis Forum recommendation on the best practices to demonstrate processed sample stability.
Bioanalysis
; 11(1): 7-11, 2019 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-30475068
8.
2018 White Paper on Recent Issues in Bioanalysis: focus on immunogenicity assays by hybrid LBA/LCMS and regulatory feedback (Part 2 - PK, PD & ADA assays by hybrid LBA/LCMS & regulatory agencies' inputs on bioanalysis, biomarkers and immunogenicity).
Bioanalysis
; 10(23): 1897-1917, 2018 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-30488729
9.
Optimization by experimental design of precursor synthesis and radiolabeling of 2-iodo-L-phenylalanine, a novel amino acid for tumor imaging.
Cancer Biother Radiopharm
; 21(3): 235-42, 2006 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-16918300
10.
Valine-based biphenylsulphonamide matrix metalloproteinase inhibitors as tumor imaging agents.
Appl Radiat Isot
; 64(6): 677-85, 2006 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-16546398
11.
2016 White Paper on recent issues in bioanalysis: focus on biomarker assay validation (BAV): (Part 2 - Hybrid LBA/LCMS and input from regulatory agencies).
Bioanalysis
; 8(23): 2457-2474, 2016 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-27855509
12.
In vivo evaluation of [(123)I]-3-(4-iodobenzyl)-1,2,3,4-tetrahydro-8-hydroxychromeno[3,4-c]pyridin-5-one: a presumed dopamine D4 receptor ligand for SPECT studies.
Nucl Med Biol
; 32(3): 293-9, 2005 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-15820765
13.
In vitro and in vivo evaluation of [123I]-VEGF165 as a potential tumor marker.
Nucl Med Biol
; 32(5): 431-6, 2005 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-15982572
14.
In vivo evaluation of [123I]-4-iodo-N-(4-(4-(2-methoxyphenyl)-piperazin-1-yl)butyl)-benzamide: a potential sigma receptor ligand for SPECT studies.
Nucl Med Biol
; 32(2): 193-200, 2005 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-15721765
15.
Tryptophane-based biphenylsulfonamide matrix metalloproteinase inhibitors as tumor imaging agents.
Cancer Biother Radiopharm
; 20(6): 639-47, 2005 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-16398616
16.
Synthesis, radiosynthesis, in vitro and preliminary in vivo evaluation of biphenyl carboxylic and hydroxamic matrix metalloproteinase (MMP) inhibitors as potential tumor imaging agents.
Appl Radiat Isot
; 62(6): 903-13, 2005 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-15799868
17.
New radioiodinated carboxylic and hydroxamic matrix metalloproteinase inhibitor tracers as potential tumor imaging agents.
Nucl Med Biol
; 31(4): 459-68, 2004 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-15093816
18.
N-alkylprotoporphyrin formation and hepatic porphyria in dogs after administration of a new antiepileptic drug candidate: mechanism and species specificity.
Toxicol Sci
; 141(2): 353-64, 2014 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-24973095
19.
In-depth study of homogeneity in DBS using two different techniques: results from the EBF DBS-microsampling consortium.
Bioanalysis
; 5(17): 2161-9, 2013 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-23829465
20.
(123)I-Interleukin-2 uptake in squamous cell carcinoma of the head and neck carcinoma.
Eur J Nucl Med Mol Imaging
; 35(2): 281-6, 2008 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-17929011