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1.
Renal Organic Anion Transporters 1 and 3 In Vitro: Gone but Not Forgotten.
Int J Mol Sci
; 24(20)2023 Oct 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-37895098
2.
Molecular Mechanisms for Species Differences in Organic Anion Transporter 1, OAT1: Implications for Renal Drug Toxicity.
Mol Pharmacol
; 94(1): 689-699, 2018 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29720497
3.
Perspective on the Application of Microphysiological Systems to Drug Transporter Studies.
Drug Metab Dispos
; 46(11): 1647-1657, 2018 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-30135246
4.
A novel multi-parametric high content screening assay in ciPTEC-OAT1 to predict drug-induced nephrotoxicity during drug discovery.
Arch Toxicol
; 92(10): 3175-3190, 2018 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-30155723
5.
A multicenter assessment of single-cell models aligned to standard measures of cell health for prediction of acute hepatotoxicity.
Arch Toxicol
; 91(3): 1385-1400, 2017 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-27344343
6.
Multiple compound-related adverse properties contribute to liver injury caused by endothelin receptor antagonists.
J Pharmacol Exp Ther
; 352(2): 281-90, 2015 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-25467130
7.
Systems toxicology: modelling biomarkers of glutathione homeostasis and paracetamol metabolism.
Drug Discov Today Technol
; 15: 9-14, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-26464084
8.
Amplifying the impact of kidney microphysiological systems: predicting renal drug clearance using mechanistic modelling based on reconstructed drug secretion.
ALTEX
; 40(3): 408-424, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-36343109
9.
Utilization of OATP1B Biomarker Coproporphyrin-I to Guide Drug-Drug Interaction Risk Assessment: Evaluation by the Pharmaceutical Industry.
Clin Pharmacol Ther
; 114(6): 1170-1183, 2023 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37750401
10.
Challenges and Opportunities for Improved Drug-Drug Interaction Predictions for Renal OCT2 and MATE1/2-K Transporters.
Clin Pharmacol Ther
; 112(3): 562-572, 2022 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35598119
11.
Leveraging microphysiological systems to address challenges encountered during development of oligonucleotide therapeutics.
ALTEX
; 39(2): 273296, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-34766620
12.
Regulation of Drug Transport Proteins-From Mechanisms to Clinical Impact: A White Paper on Behalf of the International Transporter Consortium.
Clin Pharmacol Ther
; 112(3): 461-484, 2022 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35390174
13.
The analysis of acetaminophen (paracetamol) and seven metabolites in rat, pig and human plasma by U(H)PLC-MS.
Bioanalysis
; 12(7): 485-500, 2020 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-32343149
14.
Using Quantitative Systems Toxicology to Investigate Observed Species Differences in CKA-Mediated Hepatotoxicity.
Toxicol Sci
; 166(1): 123-130, 2018 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30060248
15.
Quantification of Drug-Induced Inhibition of Canalicular Cholyl-l-Lysyl-Fluorescein Excretion From Hepatocytes by High Content Cell Imaging.
Toxicol Sci
; 148(1): 48-59, 2015 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-26220638
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