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1.
Early changes in the circulating T cells are associated with clinical outcomes after PD-L1 blockade by durvalumab in advanced NSCLC patients.
Cancer Immunol Immunother
; 70(7): 2095-2102, 2021 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-33420629
2.
Population pharmacokinetics, efficacy, and safety of moxetumomab pasudotox in patients with relapsed or refractory hairy cell leukaemia.
Br J Clin Pharmacol
; 86(7): 1367-1376, 2020 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32077130
3.
ECM components guide IL-10 producing regulatory T-cell (TR1) induction from effector memory T-cell precursors.
Proc Natl Acad Sci U S A
; 108(19): 7938-43, 2011 May 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-21518860
4.
Phase 1/2 study of monalizumab plus durvalumab in patients with advanced solid tumors.
J Immunother Cancer
; 12(2)2024 Feb 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-38309722
5.
First-in-human Phase I Trial of TPST-1120, an Inhibitor of PPARα, as Monotherapy or in Combination with Nivolumab, in Patients with Advanced Solid Tumors.
Cancer Res Commun
; 4(4): 1100-1110, 2024 Apr 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-38551394
6.
The ATR inhibitor ceralasertib potentiates cancer checkpoint immunotherapy by regulating the tumor microenvironment.
Nat Commun
; 15(1): 1700, 2024 Feb 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-38402224
7.
Modeling of Proliferating CD4 and CD8 T-Cell Changes to Tremelimumab Exposure in Patients with Unresectable Hepatocellular Carcinoma.
Clin Pharmacol Ther
; 114(4): 874-882, 2023 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-37422678
8.
Exposure-Response Analyses of Tremelimumab Monotherapy or in Combination with Durvalumab in Patients with Unresectable Hepatocellular Carcinoma.
Clin Cancer Res
; 29(4): 754-763, 2023 02 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-36477555
9.
Targeting the Inducible T-cell Costimulator (ICOS) in Patients with Relapsed/Refractory T-follicular Helper Phenotype Peripheral T-cell and Angioimmunoblastic T-cell Lymphoma.
Clin Cancer Res
; 29(10): 1869-1878, 2023 05 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36826995
10.
Maintenance of immune tolerance to a neo-self acetylcholine receptor antigen with aging: implications for late-onset autoimmunity.
J Immunol
; 184(11): 6067-75, 2010 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20435934
11.
Circulating Immune Cell and Outcome Analysis from the Phase II Study of PD-L1 Blockade with Durvalumab for Newly Diagnosed and Recurrent Glioblastoma.
Clin Cancer Res
; 28(12): 2567-2578, 2022 06 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-35395080
12.
2021 White Paper on Recent Issues in Bioanalysis: ISR for Biomarkers, Liquid Biopsies, Spectral Cytometry, Inhalation/Oral & Multispecific Biotherapeutics, Accuracy/LLOQ for Flow Cytometry (Part 2 - Recommendations on Biomarkers/CDx Assays Development & Validation, Cytometry Validation & Innovation, Biotherapeutics PK LBA Regulated Bioanalysis, Critical Reagents & Positive Controls Generation).
Bioanalysis
; 14(10): 627-692, 2022 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-35578974
13.
Assessment of seasonal influenza A virus-specific CD4 T-cell responses to 2009 pandemic H1N1 swine-origin influenza A virus.
J Virol
; 84(7): 3312-9, 2010 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-20071564
14.
Best practices for optimization and validation of flow cytometry-based receptor occupancy assays.
Cytometry B Clin Cytom
; 100(1): 63-71, 2021 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33259706
15.
Safety, Efficacy, and Pharmacodynamics of Tremelimumab Plus Durvalumab for Patients With Unresectable Hepatocellular Carcinoma: Randomized Expansion of a Phase I/II Study.
J Clin Oncol
; 39(27): 2991-3001, 2021 09 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-34292792
16.
Resistance to Durvalumab and Durvalumab plus Tremelimumab Is Associated with Functional STK11 Mutations in Patients with Non-Small Cell Lung Cancer and Is Reversed by STAT3 Knockdown.
Cancer Discov
; 11(11): 2828-2845, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34230008
17.
Short-term IL-1beta blockade reduces monocyte CD11b integrin expression in an IL-8 dependent fashion in patients with type 1 diabetes.
Clin Immunol
; 136(2): 170-3, 2010 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-20483667
18.
Safety and Clinical Activity of MEDI1873, a Novel GITR Agonist, in Advanced Solid Tumors.
Clin Cancer Res
; 26(23): 6196-6203, 2020 12 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32887725
19.
Changes in autoreactive T cell avidity during type 1 diabetes development.
Clin Immunol
; 132(3): 312-20, 2009 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-19482555
20.
Moxetumomab pasudotox in relapsed/refractory hairy cell leukemia.
Leukemia
; 32(8): 1768-1777, 2018 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-30030507