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1.
Non-stereo-selective cytosolic human brain tissue 3-ketosteroid reductase is refractory to inhibition by AKR1C inhibitors.
Biochim Biophys Acta
; 1801(11): 1221-31, 2010 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-20673851
2.
Expression of estrogen receptor alpha increases leptin-induced STAT3 activity in breast cancer cells.
Int J Cancer
; 127(1): 55-66, 2010 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19876927
3.
Potential, pitfalls, and prospects of food allergy diagnostics with recombinant allergens or synthetic sequential epitopes.
J Allergy Clin Immunol
; 121(6): 1323-30, 2008 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-18472149
4.
An indomethacin analogue, N-(4-chlorobenzoyl)-melatonin, is a selective inhibitor of aldo-keto reductase 1C3 (type 2 3alpha-HSD, type 5 17beta-HSD, and prostaglandin F synthase), a potential target for the treatment of hormone dependent and hormone independent malignancies.
Biochem Pharmacol
; 75(2): 484-93, 2008 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-17950253
5.
Identification of the major oxidative 3alpha-hydroxysteroid dehydrogenase in human prostate that converts 5alpha-androstane-3alpha,17beta-diol to 5alpha-dihydrotestosterone: a potential therapeutic target for androgen-dependent disease.
Mol Endocrinol
; 20(2): 444-58, 2006 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-16179381
6.
Transcript profiling of the androgen signal in normal prostate, benign prostatic hyperplasia, and prostate cancer.
Endocrinology
; 147(12): 5806-16, 2006 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-16959841
7.
Aldo-keto reductase (AKR) 1C3: role in prostate disease and the development of specific inhibitors.
Mol Cell Endocrinol
; 248(1-2): 182-91, 2006 Mar 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-16417966
8.
Human type 3 3alpha-hydroxysteroid dehydrogenase (aldo-keto reductase 1C2) and androgen metabolism in prostate cells.
Endocrinology
; 144(7): 2922-32, 2003 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-12810547
9.
Dithioerythritol (DTE) prevents inhibitory effects of triphenyltin (TPT) on the key enzymes of the human sex steroid hormone metabolism.
J Steroid Biochem Mol Biol
; 84(5): 569-76, 2003 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-12767282
10.
Characterisation of estrogenic 17beta-hydroxysteroid dehydrogenase (17beta-HSD) activity in the human brain.
J Steroid Biochem Mol Biol
; 86(1): 79-92, 2003 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-12943747
11.
The roles of aldo-keto reductases in steroid hormone action.
Drug News Perspect
; 17(9): 563-78, 2004 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-15645014
12.
Allopregnanolone serum levels and expression of 5 alpha-reductase and 3 alpha-hydroxysteroid dehydrogenase isoforms in hippocampal and temporal cortex of patients with epilepsy.
Epilepsy Res
; 54(1): 11-9, 2003 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-12742591
13.
Effects of butyltins on human 5alpha-reductase type 1 and type 2 activity.
Steroids
; 67(10): 859-67, 2002 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-12231121
14.
Characterization of a monoclonal antibody for human aldo-keto reductase AKR1C3 (type 2 3alpha-hydroxysteroid dehydrogenase/type 5 17beta-hydroxysteroid dehydrogenase); immunohistochemical detection in breast and prostate.
Steroids
; 69(13-14): 795-801, 2004 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-15582534
15.
Tibolone metabolism in human liver is catalyzed by 3alpha/3beta-hydroxysteroid dehydrogenase activities of the four isoforms of the aldo-keto reductase (AKR)1C subfamily.
J Pharmacol Exp Ther
; 316(3): 1300-9, 2006 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-16339391
16.
Infection of barley roots by Chaetomium globosum: evidence for a protective role of the exodermis.
Mycol Res
; 107(Pt 9): 1094-102, 2003 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-14563137
17.
Human cytosolic 3alpha-hydroxysteroid dehydrogenases of the aldo-keto reductase superfamily display significant 3beta-hydroxysteroid dehydrogenase activity: implications for steroid hormone metabolism and action.
J Biol Chem
; 279(11): 10784-95, 2004 Mar 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-14672942
18.
Tibolone is metabolized by the 3alpha/3beta-hydroxysteroid dehydrogenase activities of the four human isozymes of the aldo-keto reductase 1C subfamily: inversion of stereospecificity with a delta5(10)-3-ketosteroid.
Mol Pharmacol
; 66(6): 1702-11, 2004 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-15383625
19.
Four additional CLCN5 exons encode a widely expressed novel long CLC-5 isoform but fail to explain Dent's phenotype in patients without mutations in the short variant.
Kidney Blood Press Res
; 26(3): 176-84, 2003.
Artículo
en Inglés
| MEDLINE | ID: mdl-12886045
20.
Steroid sulfatase (STS) expression in the human temporal lobe: enzyme activity, mRNA expression and immunohistochemistry study.
J Neurochem
; 89(2): 403-17, 2004 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-15056284