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1.
Randomized phase 1 study of the phosphatidylinositol 3-kinase δ inhibitor idelalisib in patients with allergic rhinitis.
J Allergy Clin Immunol
; 137(6): 1733-1741, 2016 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-26915677
2.
Inhibition of PI3Kδ reduces kidney infiltration by macrophages and ameliorates systemic lupus in the mouse.
J Immunol
; 193(2): 544-54, 2014 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24935930
3.
Effects of isoform-selective phosphatidylinositol 3-kinase inhibitors on osteoclasts: actions on cytoskeletal organization, survival, and resorption.
J Biol Chem
; 288(49): 35346-57, 2013 Dec 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-24133210
4.
CAL-101, a p110delta selective phosphatidylinositol-3-kinase inhibitor for the treatment of B-cell malignancies, inhibits PI3K signaling and cellular viability.
Blood
; 117(2): 591-4, 2011 Jan 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-20959606
5.
Biochemical characterization of tirabrutinib and other irreversible inhibitors of Bruton's tyrosine kinase reveals differences in on - and off - target inhibition.
Biochim Biophys Acta Gen Subj
; 1864(4): 129531, 2020 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-31953125
6.
Dose-Dependent Suppression of Cytokine production from T cells by a Novel Phosphoinositide 3-Kinase Delta Inhibitor.
Sci Rep
; 6: 30384, 2016 07 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-27461849
7.
Discovery of Orally Efficacious Phosphoinositide 3-Kinase δ Inhibitors with Improved Metabolic Stability.
J Med Chem
; 59(19): 9228-9242, 2016 Oct 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-27660855
8.
2,4,6-Triaminopyrimidine as a Novel Hinge Binder in a Series of PI3Kδ Selective Inhibitors.
J Med Chem
; 59(7): 3532-48, 2016 Apr 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-26980109
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