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1.
Completion of the Total Synthesis of Several Bioactive Sarpagine/Macroline Alkaloids including the Important NF-κB Inhibitor N4-Methyltalpinine.
Molecules
; 27(5)2022 Mar 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-35268836
2.
Modulating native GABAA receptors in medulloblastoma with positive allosteric benzodiazepine-derivatives induces cell death.
J Neurooncol
; 142(3): 411-422, 2019 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-30725256
3.
Evidence That Sedative Effects of Benzodiazepines Involve Unexpected GABAA Receptor Subtypes: Quantitative Observation Studies in Rhesus Monkeys.
J Pharmacol Exp Ther
; 366(1): 145-157, 2018 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29720564
4.
A Novel Orally Available Asthma Drug Candidate That Reduces Smooth Muscle Constriction and Inflammation by Targeting GABAA Receptors in the Lung.
Mol Pharm
; 15(5): 1766-1777, 2018 05 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29578347
5.
eEF2K/eEF2 Pathway Controls the Excitation/Inhibition Balance and Susceptibility to Epileptic Seizures.
Cereb Cortex
; 27(3): 2226-2248, 2017 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27005990
6.
Concise Total Synthesis of (-)-Affinisine Oxindole, (+)-Isoalstonisine, (+)-Alstofoline, (-)-Macrogentine, (+)-Na -Demethylalstonisine, (-)-Alstonoxineâ A, and (+)-Alstonisine.
Chemistry
; 23(62): 15805-15819, 2017 Nov 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28875520
7.
Alleviation of Multiple Asthmatic Pathologic Features with Orally Available and Subtype Selective GABAA Receptor Modulators.
Mol Pharm
; 14(6): 2088-2098, 2017 06 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-28440659
8.
Targeting the γ-Aminobutyric Acid A Receptor α4 Subunit in Airway Smooth Muscle to Alleviate Bronchoconstriction.
Am J Respir Cell Mol Biol
; 54(4): 546-53, 2016 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-26405827
9.
Correction to "A Novel Orally Available Asthma Drug Candidate That Reduces Smooth Muscle Constriction and Inflammation by Targeting GABAA Receptors in the Lung".
Mol Pharm
; 16(11): 4756, 2019 Nov 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-31633359
10.
A facile synthesis and discovery of highly functionalized tetrahydro-pyridines and pyridines as antimycobacterial agents.
Chem Pharm Bull (Tokyo)
; 58(5): 602-10, 2010 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-20460783
11.
Novel Benzodiazepine-Like Ligands with Various Anxiolytic, Antidepressant, or Pro-Cognitive Profiles.
Mol Neuropsychiatry
; 5(2): 84-97, 2019 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-31192221
12.
Brain Vacuolation Resulting From Administration of the Type II Ampakine CX717 Is An Artifact Related to Molecular Structure and Chemical Reaction With Tissue Fixative Agents.
Toxicol Sci
; 162(2): 383-395, 2018 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29253237
13.
Attaining in vivo selectivity of positive modulation of α3ßγ2 GABAA receptors in rats: A hard task!
Eur Neuropsychopharmacol
; 28(8): 903-914, 2018 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-29891214
14.
Effects of the benzodiazepine GABAA α1-preferring antagonist 3-isopropoxy-ß-carboline hydrochloride (3-ISOPBC) on alcohol seeking and self-administration in baboons.
Drug Alcohol Depend
; 170: 25-31, 2017 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27865151
15.
Optimization of substituted imidazobenzodiazepines as novel asthma treatments.
Eur J Med Chem
; 126: 550-560, 2017 Jan 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-27915170
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