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1.
Aurora kinase A inhibitor, LY3295668 erbumine: a phase 1 monotherapy safety study in patients with locally advanced or metastatic solid tumors.
Invest New Drugs
; 39(4): 1001-1010, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-33479856
2.
Prognostic and predictive value of circulating tumor cells and CXCR4 expression as biomarkers for a CXCR4 peptide antagonist in combination with carboplatin-etoposide in small cell lung cancer: exploratory analysis of a phase II study.
Invest New Drugs
; 35(3): 334-344, 2017 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-28299514
3.
The Genomic Landscape of Intrinsic and Acquired Resistance to Cyclin-Dependent Kinase 4/6 Inhibitors in Patients with Hormone Receptor-Positive Metastatic Breast Cancer.
Cancer Discov
; 10(8): 1174-1193, 2020 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-32404308
4.
A randomized clinical efficacy study targeting mPGES1 or EP4 in dogs with spontaneous osteoarthritis.
Sci Transl Med
; 11(516)2019 10 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-31666405
5.
A randomized phase II study of LY2510924 and carboplatin/etoposide versus carboplatin/etoposide in extensive-disease small cell lung cancer.
Lung Cancer
; 105: 7-13, 2017 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-28236984
6.
Distinct mobilization of leukocytes and hematopoietic stem cells by CXCR4 peptide antagonist LY2510924 and monoclonal antibody LY2624587.
Oncotarget
; 8(55): 94619-94634, 2017 Nov 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29212254
7.
A Randomized, Open-Label Phase 2 Study of the CXCR4 Inhibitor LY2510924 in Combination with Sunitinib Versus Sunitinib Alone in Patients with Metastatic Renal Cell Carcinoma (RCC).
Target Oncol
; 11(5): 643-653, 2016 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-27154357
8.
A decade of innovation in pharmaceutical R&D: the Chorus model.
Nat Rev Drug Discov
; 14(1): 17-28, 2015 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-25503514
9.
Discovery of 6-(4-{[5-Cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl]methoxy}piperidin-1-yl)-1-methyl-1H-indole-3-carboxylic Acid: A Novel FXR Agonist for the Treatment of Dyslipidemia.
J Med Chem
; 58(24): 9768-72, 2015 Dec 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-26568144
10.
A phase I trial of LY2510924, a CXCR4 peptide antagonist, in patients with advanced cancer.
Clin Cancer Res
; 20(13): 3581-8, 2014 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24727324
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