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1.
Rapid depolarization and cytosolic calcium increase go hand-in-hand in mesophyll cells' ozone response.
New Phytol
; 232(4): 1692-1702, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34482538
2.
A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm.
Toxicol Appl Pharmacol
; 394: 114961, 2020 05 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32209365
3.
Repolarization studies using human stem cell-derived cardiomyocytes: Validation studies and best practice recommendations.
Regul Toxicol Pharmacol
; 117: 104756, 2020 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-32822771
4.
Corrigendum to "A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm" [Toxicology and Applied Pharmacology volume 394C (2020) 114961].
Toxicol Appl Pharmacol
; 395: 114983, 2020 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32247767
5.
Reliable identification of cardiac conduction abnormalities in drug discovery using automated patch clamp II: Best practices for Nav1.5 peak current in a high throughput screening environment.
J Pharmacol Toxicol Methods
; 112: 107125, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34500078
6.
Integration of mechanical conditioning into a high throughput contractility assay for cardiac safety assessment.
J Pharmacol Toxicol Methods
; 105: 106892, 2020 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-32629160
7.
Reliable identification of cardiac liability in drug discovery using automated patch clamp: Benchmarking best practices and calibration standards for improved proarrhythmic assessment.
J Pharmacol Toxicol Methods
; 105: 106884, 2020 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-32565325
8.
A general procedure to select calibration drugs for lab-specific validation and calibration of proarrhythmia risk prediction models: An illustrative example using the CiPA model.
J Pharmacol Toxicol Methods
; 105: 106890, 2020 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-32574700
9.
Publisher Correction: Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells.
Sci Rep
; 10(1): 11884, 2020 Jul 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-32665705
10.
Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells.
Sci Rep
; 10(1): 5627, 2020 03 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-32221320
11.
Cross - site comparison of excitation-contraction coupling using impedance and field potential recordings in hiPSC cardiomyocytes.
J Pharmacol Toxicol Methods
; 93: 46-58, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29940218
12.
A Hybrid Model for Safety Pharmacology on an Automated Patch Clamp Platform: Using Dynamic Clamp to Join iPSC-Derived Cardiomyocytes and Simulations of Ik1 Ion Channels in Real-Time.
Front Physiol
; 8: 1094, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-29403387
13.
Mechanisms of acquired long QT syndrome in patients with propionic academia.
Heart Rhythm
; 13(6): 1335-45, 2016 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-26854997
14.
Identification of Drug-Drug Interactions In Vitro: A Case Study Evaluating the Effects of Sofosbuvir and Amiodarone on hiPSC-Derived Cardiomyocytes.
Toxicol Sci
; 154(1): 174-182, 2016 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-27503387
15.
New easy-to-use hybrid system for extracellular potential and impedance recordings.
J Lab Autom
; 20(2): 175-88, 2015 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-25532527
16.
State-of-the-art automated patch clamp: heat activation, action potentials, and high throughput in ion channel screening.
Methods Mol Biol
; 1183: 65-80, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-25023302
17.
Automated Patch Clamp Analysis of nAChα7 and Na(V)1.7 Channels.
Curr Protoc Pharmacol
; 65: 11.13.1-48, 2014 Jun 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-24934604
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