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1.
CK-2127107 amplifies skeletal muscle response to nerve activation in humans.
Muscle Nerve
; 57(5): 729-734, 2018 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29150952
2.
The Absolute Bioavailability and Effect of Food on the Pharmacokinetics of Odanacatib: A Stable-Label i.v./Oral Study in Healthy Postmenopausal Women.
Drug Metab Dispos
; 44(9): 1450-8, 2016 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-27402726
3.
Determining pharmacological selectivity of the kappa opioid receptor antagonist LY2456302 using pupillometry as a translational biomarker in rat and human.
Int J Neuropsychopharmacol
; 18(2)2014 Oct 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-25637376
4.
Tirasemtiv amplifies skeletal muscle response to nerve activation in humans.
Muscle Nerve
; 50(6): 925-31, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-24634285
5.
Safety, Pharmacokinetics, and Pharmacodynamics of Trazpiroben (TAK-906), a Novel Selective D2 /D3 Receptor Antagonist: A Phase 1 Randomized, Placebo-Controlled Single- and Multiple-Dose Escalation Study in Healthy Participants.
Clin Pharmacol Drug Dev
; 10(8): 927-939, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-33462988
6.
Metabolic disposition of [14C]bazedoxifene in healthy postmenopausal women.
Drug Metab Dispos
; 37(6): 1219-25, 2009 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-19273530
7.
A thorough QTc study to assess the effect of sitagliptin, a DPP4 inhibitor, on ventricular repolarization in healthy subjects.
J Clin Pharmacol
; 49(8): 937-46, 2009 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-19602719
8.
Effect of casopitant, a novel NK-1 antagonist, on the pharmacokinetics of dolasetron and granisetron.
Support Care Cancer
; 17(9): 1187-93, 2009 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-19205754
9.
Minimal pharmacokinetic interaction between the human immunodeficiency virus nonnucleoside reverse transcriptase inhibitor etravirine and the integrase inhibitor raltegravir in healthy subjects.
Antimicrob Agents Chemother
; 52(12): 4228-32, 2008 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-18838586
10.
Safety, pharmacokinetics, and immunogenicity of a co-formulated cocktail of three human monoclonal antibodies targeting Ebola virus glycoprotein in healthy adults: a randomised, first-in-human phase 1 study.
Lancet Infect Dis
; 18(8): 884-893, 2018 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-29929783
11.
A Randomized Phase 1 Dose Escalation Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Trabodenoson in Healthy Adult Volunteers.
J Ocul Pharmacol Ther
; 32(8): 548-554, 2016 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-27046445
12.
Inhaled loxapine and intramuscular lorazepam in healthy volunteers: a randomized placebo-controlled drug-drug interaction study.
Pharmacol Res Perspect
; 3(6): e00194, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-27022468
13.
Effect of ponesimod, a selective S1P1 receptor modulator, on the QT interval in healthy individuals.
Basic Clin Pharmacol Toxicol
; 116(5): 429-37, 2015 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-25287214
14.
A thorough QT study in the context of an uptitration regimen with selexipag, a selective oral prostacyclin receptor agonist.
Drug Des Devel Ther
; 9: 175-85, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25552906
15.
Effect of ceralifimod (ONO-4641) on lymphocytes and cardiac function: Randomized, double-blind, placebo-controlled trial with an open-label fingolimod arm.
J Clin Pharmacol
; 55(9): 1051-60, 2015 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-25855155
16.
Pharmacokinetic and safety evaluation of palonosetron, a 5-hydroxytryptamine-3 receptor antagonist, in U.S. and Japanese healthy subjects.
J Clin Pharmacol
; 44(5): 520-31, 2004 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-15102873
17.
Safety, tolerability, and pharmacokinetic evaluation of single- and multiple-ascending doses of a novel kappa opioid receptor antagonist LY2456302 and drug interaction with ethanol in healthy subjects.
J Clin Pharmacol
; 54(9): 968-78, 2014 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-24619932
18.
Multiple-dose pharmacokinetics and pharmacodynamics of sergliflozin etabonate, a novel inhibitor of glucose reabsorption, in healthy overweight and obese subjects: a randomized double-blind study.
J Clin Pharmacol
; 50(6): 636-46, 2010 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-20200268
19.
Effects of age, gender, and race/ethnicity on the pharmacokinetics of posaconazole in healthy volunteers.
Antimicrob Agents Chemother
; 51(2): 495-502, 2007 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-17101682
20.
Pharmacokinetics, metabolism and excretion of intravenous [l4C]-palonosetron in healthy human volunteers.
Biopharm Drug Dispos
; 25(8): 329-37, 2004 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-15378559