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1.
Characterizing Intra-Tumor and Inter-Tumor Variability of Immune Cell Infiltrates in Murine Syngeneic Tumors.
Am J Pathol
; 191(12): 2133-2146, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34428423
2.
Novel potent dual inhibitors of CK2 and Pim kinases with antiproliferative activity against cancer cells.
Bioorg Med Chem Lett
; 22(9): 3327-31, 2012 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22460033
3.
Pre-clinical characterization of CX-4945, a potent and selective small molecule inhibitor of CK2 for the treatment of cancer.
Mol Cell Biochem
; 356(1-2): 37-43, 2011 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-21755459
4.
Novel potent pyrimido[4,5-c]quinoline inhibitors of protein kinase CK2: SAR and preliminary assessment of their analgesic and anti-viral properties.
Bioorg Med Chem Lett
; 21(6): 1687-91, 2011 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21316963
5.
7-(4H-1,2,4-Triazol-3-yl)benzo[c][2,6]naphthyridines: a novel class of Pim kinase inhibitors with potent cell antiproliferative activity.
Bioorg Med Chem Lett
; 21(22): 6687-92, 2011 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21982499
6.
Characterization of the Selective Indoleamine 2,3-Dioxygenase-1 (IDO1) Catalytic Inhibitor EOS200271/PF-06840003 Supports IDO1 as a Critical Resistance Mechanism to PD-(L)1 Blockade Therapy.
Mol Cancer Ther
; 17(12): 2530-2542, 2018 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-30232146
7.
CK2 inhibitor CX-4945 suppresses DNA repair response triggered by DNA-targeted anticancer drugs and augments efficacy: mechanistic rationale for drug combination therapy.
Mol Cancer Ther
; 11(4): 994-1005, 2012 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-22267551
8.
Combined inhibition of EGFR and CK2 augments the attenuation of PI3K-Akt-mTOR signaling and the killing of cancer cells.
Cancer Lett
; 322(1): 113-8, 2012 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22387988
9.
Discovery of CX-6258. A Potent, Selective, and Orally Efficacious pan-Pim Kinases Inhibitor.
ACS Med Chem Lett
; 3(2): 135-9, 2012 Feb 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-24900437
10.
Targeting RNA polymerase I with an oral small molecule CX-5461 inhibits ribosomal RNA synthesis and solid tumor growth.
Cancer Res
; 71(4): 1418-30, 2011 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21159662
11.
Discovery and SAR of 5-(3-chlorophenylamino)benzo[c][2,6]naphthyridine-8-carboxylic acid (CX-4945), the first clinical stage inhibitor of protein kinase CK2 for the treatment of cancer.
J Med Chem
; 54(2): 635-54, 2011 Jan 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-21174434
12.
CX-4945, an orally bioavailable selective inhibitor of protein kinase CK2, inhibits prosurvival and angiogenic signaling and exhibits antitumor efficacy.
Cancer Res
; 70(24): 10288-98, 2010 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21159648
13.
Design and synthesis of an expanded porphyrin that has selectivity for the c-MYC G-quadruplex structure.
J Am Chem Soc
; 127(9): 2944-59, 2005 Mar 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-15740131
14.
Early placental insulin-like protein (INSL4 or EPIL) in placental and fetal membrane growth.
Biol Reprod
; 73(4): 695-702, 2005 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-15958731
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