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1.
SORL1 is a receptor for tau that promotes tau seeding.
J Biol Chem
; 300(6): 107313, 2024 Apr 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-38657864
2.
Regulation of tau internalization, degradation, and seeding by LRP1 reveals multiple pathways for tau catabolism.
J Biol Chem
; 296: 100715, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-33930462
3.
Molecular chaperone RAP interacts with LRP1 in a dynamic bivalent mode and enhances folding of ligand-binding regions of other LDLR family receptors.
J Biol Chem
; 297(1): 100842, 2021 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-34058195
4.
High-affinity binding of plasminogen-activator inhibitor 1 complexes to LDL receptor-related protein 1 requires lysines 80, 88, and 207.
J Biol Chem
; 295(1): 212-222, 2020 01 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-31792055
5.
Moderate aerobic exercise prevents matrix degradation and death in a mouse model of aortic dissection and aneurysm.
Am J Physiol Heart Circ Physiol
; 320(5): H1786-H1801, 2021 05 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33635167
6.
High-Affinity Binding of LDL Receptor-Related Protein 1 to Matrix Metalloprotease 1 Requires Protease:Inhibitor Complex Formation.
Biochemistry
; 59(32): 2922-2933, 2020 08 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-32702237
7.
LRP1 (Low-Density Lipoprotein Receptor-Related Protein 1) Regulates Smooth Muscle Contractility by Modulating Ca2+ Signaling and Expression of Cytoskeleton-Related Proteins.
Arterioscler Thromb Vasc Biol
; 38(11): 2651-2664, 2018 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-30354243
8.
Macrophage LRP1 Promotes Diet-Induced Hepatic Inflammation and Metabolic Dysfunction by Modulating Wnt Signaling.
Mediators Inflamm
; 2018: 7902841, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-30524198
9.
High Affinity Binding of the Receptor-associated Protein D1D2 Domains with the Low Density Lipoprotein Receptor-related Protein (LRP1) Involves Bivalent Complex Formation: CRITICAL ROLES OF LYSINES 60 AND 191.
J Biol Chem
; 291(35): 18430-9, 2016 08 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-27402839
10.
Evidence That Factor VIII Forms a Bivalent Complex with the Low Density Lipoprotein (LDL) Receptor-related Protein 1 (LRP1): IDENTIFICATION OF CLUSTER IV ON LRP1 AS THE MAJOR BINDING SITE.
J Biol Chem
; 291(50): 26035-26044, 2016 Dec 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-27794518
11.
Engineered Tissue Inhibitor of Metalloproteinases-3 Variants Resistant to Endocytosis Have Prolonged Chondroprotective Activity.
J Biol Chem
; 291(42): 22160-22172, 2016 Oct 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-27582494
12.
Microglial-mediated PDGF-CC activation increases cerebrovascular permeability during ischemic stroke.
Acta Neuropathol
; 134(4): 585-604, 2017 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-28725968
13.
Regulation of Itch and Nedd4 E3 Ligase Activity and Degradation by LRAD3.
Biochemistry
; 55(8): 1204-13, 2016 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26854353
14.
Generation of a Potent Low Density Lipoprotein Receptor-related Protein 1 (LRP1) Antagonist by Engineering a Stable Form of the Receptor-associated Protein (RAP) D3 Domain.
J Biol Chem
; 290(28): 17262-8, 2015 Jul 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-26013822
15.
Mac-1 Regulates IL-13 Activity in Macrophages by Directly Interacting with IL-13Rα1.
J Biol Chem
; 290(35): 21642-51, 2015 Aug 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-26160172
16.
Smooth muscle cell deletion of low-density lipoprotein receptor-related protein 1 augments angiotensin II-induced superior mesenteric arterial and ascending aortic aneurysms.
Arterioscler Thromb Vasc Biol
; 35(1): 155-62, 2015 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-25395615
17.
Low density lipoprotein receptor-related protein 1 (LRP1)-mediated endocytic clearance of a disintegrin and metalloproteinase with thrombospondin motifs-4 (ADAMTS-4): functional differences of non-catalytic domains of ADAMTS-4 and ADAMTS-5 in LRP1 binding.
J Biol Chem
; 289(10): 6462-6474, 2014 Mar 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-24474687
18.
Tissue-type plasminogen activator suppresses activated stellate cells through low-density lipoprotein receptor-related protein 1.
Lab Invest
; 95(10): 1117-29, 2015 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-26237273
19.
Low-density lipoprotein receptor-related protein-1: role in the regulation of vascular integrity.
Arterioscler Thromb Vasc Biol
; 34(3): 487-98, 2014 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-24504736
20.
Differential regulation of extracellular tissue inhibitor of metalloproteinases-3 levels by cell membrane-bound and shed low density lipoprotein receptor-related protein 1.
J Biol Chem
; 288(1): 332-42, 2013 Jan 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-23166318