Detalles de la búsqueda
1.
iBodies: Modular Synthetic Antibody Mimetics Based on Hydrophilic Polymers Decorated with Functional Moieties.
Angew Chem Int Ed Engl
; 55(7): 2356-60, 2016 Feb 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-26749427
2.
Anti-Lymphoma Efficacy Comparison of Anti-Cd20 Monoclonal Antibody-Targeted and Non-Targeted Star-Shaped Polymer-Prodrug Conjugates.
Molecules
; 20(11): 19849-64, 2015 Nov 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-26556320
3.
Antitumor activity of IL-2/anti-IL-2 mAb immunocomplexes exerts synergism with that of N-(2-hydroxypropyl)methacrylamide copolymer-bound doxorubicin conjugate due to its low immunosuppressive activity.
Int J Cancer
; 129(8): 2002-12, 2011 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21165950
4.
Poly[N-(2-hydroxypropyl)methacrylamide]-based tissue-embedding medium compatible with MALDI mass spectrometry imaging experiments.
Anal Chem
; 83(13): 5458-62, 2011 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21634803
5.
Interaction of N-(2-hydroxypropyl)methacrylamide copolymer-doxorubicin conjugates with human liver microsomal cytochromes P450: comparison with free doxorubicin.
Drug Metab Dispos
; 39(9): 1704-10, 2011 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-21642392
6.
Doxorubicin attached to HPMA copolymer via amide bond modifies the glycosylation pattern of EL4 cells.
Tumour Biol
; 31(4): 233-42, 2010 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-20556593
7.
The structure of polymer carriers controls the efficacy of the experimental combination treatment of tumors with HPMA copolymer conjugates carrying doxorubicin and docetaxel.
J Control Release
; 246: 1-11, 2017 01 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-27940304
8.
Overcoming multidrug resistance via simultaneous delivery of cytostatic drug and P-glycoprotein inhibitor to cancer cells by HPMA copolymer conjugate.
Biomaterials
; 115: 65-80, 2017 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27886555
9.
HPMA based macromolecular therapeutics: internalization, intracellular pathway and cell death depend on the character of covalent bond between the drug and the peptidic spacer and also on spacer composition.
J Drug Target
; 14(6): 391-403, 2006 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-17092839
10.
The structure-dependent toxicity, pharmacokinetics and anti-tumour activity of HPMA copolymer conjugates in the treatment of solid tumours and leukaemia.
J Control Release
; 223: 1-10, 2016 Feb 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-26708020
11.
Chemotherapy based on HPMA copolymer conjugates with pH-controlled release of doxorubicin triggers anti-tumor immunity.
J Control Release
; 110(1): 119-29, 2005 Dec 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-16269198
12.
Novel IL-2-Poly(HPMA)Nanoconjugate Based Immunotherapy.
J Biomed Nanotechnol
; 11(9): 1662-73, 2015 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-26485935
13.
Cytostatic and immunomobilizing activities of polymer-bound drugs: experimental and first clinical data.
J Control Release
; 91(1-2): 1-16, 2003 Aug 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-12932633
14.
HPMA copolymer-doxorubicin conjugates: The effects of molecular weight and architecture on biodistribution and in vivo activity.
J Control Release
; 164(3): 346-54, 2012 Dec 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-22759979
15.
Biodegradable star HPMA polymer-drug conjugates: Biodegradability, distribution and anti-tumor efficacy.
J Control Release
; 154(3): 241-8, 2011 Sep 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-21699933
16.
Biodegradable star HPMA polymer conjugates of doxorubicin for passive tumor targeting.
Eur J Pharm Sci
; 42(5): 527-39, 2011 Apr 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-21392579
17.
Spectral analysis of doxorubicin accumulation and the indirect quantification of its DNA intercalation.
Eur J Pharm Biopharm
; 76(3): 514-24, 2010 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-20638475
18.
Drug-HPMA-HuIg conjugates effective against human solid cancer.
Adv Exp Med Biol
; 519: 125-43, 2003.
Artículo
en Inglés
| MEDLINE | ID: mdl-12675212
19.
HPMA copolymer conjugates with reduced anti-CD20 antibody for cell-specific drug targeting. I. Synthesis and in vitro evaluation of binding efficacy and cytostatic activity.
J Control Release
; 140(1): 18-26, 2009 Nov 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-19632282
20.
Overcoming immunoescape mechanisms of BCL1 leukemia and induction of CD8+ T-cell-mediated BCL1-specific resistance in mice cured by targeted polymer-bound doxorubicin.
Cancer Res
; 68(23): 9875-83, 2008 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19047168