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1.
Mechanistic Insight into NMDA Receptor Dysregulation by Rare Variants in the GluN2A and GluN2B Agonist Binding Domains.
Am J Hum Genet
; 99(6): 1261-1280, 2016 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27839871
2.
The Bioactive Protein-Ligand Conformation of GluN2C-Selective Positive Allosteric Modulators Bound to the NMDA Receptor.
Mol Pharmacol
; 93(2): 141-156, 2018 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-29242355
3.
GluN2D-Containing N-methyl-d-Aspartate Receptors Mediate Synaptic Transmission in Hippocampal Interneurons and Regulate Interneuron Activity.
Mol Pharmacol
; 90(6): 689-702, 2016 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-27625038
4.
Distinct GluN1 and GluN2 Structural Determinants for Subunit-Selective Positive Allosteric Modulation of N-Methyl-d-aspartate Receptors.
ACS Chem Neurosci
; 12(1): 79-98, 2021 01 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33326224
5.
Discovery of Dihydropyrrolo[1,2-a]pyrazin-3(4H)-one-Based Second-Generation GluN2C- and GluN2D-Selective Positive Allosteric Modulators (PAMs) of the N-Methyl-d-Aspartate (NMDA) Receptor.
J Med Chem
; 63(14): 7569-7600, 2020 07 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-32538088
6.
The Structure-Activity Relationship of a Tetrahydroisoquinoline Class of N-Methyl-d-Aspartate Receptor Modulators that Potentiates GluN2B-Containing N-Methyl-d-Aspartate Receptors.
J Med Chem
; 60(13): 5556-5585, 2017 07 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-28586221
7.
NMDA receptor modulators: an updated patent review (2013-2014).
Expert Opin Ther Pat
; 24(12): 1349-66, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-25351527
8.
Synthesis and structure activity relationship of tetrahydroisoquinoline-based potentiators of GluN2C and GluN2D containing N-methyl-D-aspartate receptors.
J Med Chem
; 56(13): 5351-81, 2013 Jul 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-23627311
9.
Novel NMDA receptor modulators: an update.
Expert Opin Ther Pat
; 22(11): 1337-52, 2012 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-23009122
10.
Correction to Synthesis and Structure Activity Relationship of Tetrahydroisoquinoline-Based Potentiators of GluN2C and GluN2D Containing N-Methyl-d-aspartate Receptors.
J Med Chem
; 57(11): 4975, 2014 Jun 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-24878076
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