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1.
Hydroxyurea treatment is associated with lower malaria incidence in children with sickle cell anemia in sub-Saharan Africa.
Blood
; 141(12): 1402-1410, 2023 03 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-36375125
2.
Reducing transfusion utilization for children with sickle cell anemia in sub-Saharan Africa with hydroxyurea: Analysis from the phase I/II REACH trial.
Am J Hematol
; 99(4): 625-632, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-38332651
3.
Pharmacokinetic-guided hydroxyurea to reduce transfusions in Ugandan children with sickle cell anemia: study design of the Alternative Dosing And Prevention of Transfusions (ADAPT) trial.
Acta Haematol
; 2024 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-38824918
4.
Stroke Prevention with Hydroxyurea Enabled through Research and Education: A Phase 2 Primary Stroke Prevention Trial in Sub-Saharan Africa.
Acta Haematol
; 146(2): 95-105, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-35977532
5.
Hydroxyurea for Children with Sickle Cell Anemia in Sub-Saharan Africa.
N Engl J Med
; 380(2): 121-131, 2019 01 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-30501550
6.
Hydroxycarbamide versus chronic transfusion for maintenance of transcranial doppler flow velocities in children with sickle cell anaemia-TCD With Transfusions Changing to Hydroxyurea (TWiTCH): a multicentre, open-label, phase 3, non-inferiority trial.
Lancet
; 387(10019): 661-670, 2016 Feb 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-26670617
7.
Hydroxyurea dose optimisation for children with sickle cell anaemia in sub-Saharan Africa (REACH): extended follow-up of a multicentre, open-label, phase 1/2 trial.
Lancet Haematol
; 11(6): e425-e435, 2024 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-38701812
8.
Hydroxyurea with dose escalation for primary stroke risk reduction in children with sickle cell anaemia in Tanzania (SPHERE): an open-label, phase 2 trial.
Lancet Haematol
; 10(4): e261-e271, 2023 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-36870358
9.
Prospective identification of variables as outcomes for treatment (PIVOT): study protocol for a randomised, placebo-controlled trial of hydroxyurea for Ghanaian children and adults with haemoglobin SC disease.
Trials
; 24(1): 603, 2023 Sep 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-37737189
10.
Stroke Avoidance for Children in REpública Dominicana (SACRED): Protocol for a Prospective Study of Stroke Risk and Hydroxyurea Treatment in Sickle Cell Anemia.
JMIR Res Protoc
; 6(6): e107, 2017 Jun 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-28576754
11.
EXpanding Treatment for Existing Neurological Disease (EXTEND): An Open-Label Phase II Clinical Trial of Hydroxyurea Treatment in Sickle Cell Anemia.
JMIR Res Protoc
; 5(3): e185, 2016 Sep 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-27619954
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