Detalles de la búsqueda
1.
A fully human monoclonal antibody possesses antibody-dependent cellular cytotoxicity (ADCC) activity against the H1 subtype of influenza A virus by targeting a conserved epitope at the HA1 protomer interface.
J Med Virol
; 95(7): e28901, 2023 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-37394780
2.
Increased Antibody Avidity and Cross-Neutralization of Severe Acute Respiratory Syndrome Coronavirus 2 Variants by Hyperimmunized Transchromosomic Bovine-Derived Human Immunoglobulins for Treatment of Coronavirus Disease 2019.
J Infect Dis
; 226(4): 655-663, 2022 09 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-35106573
3.
Human Monoclonal Antibody Derived from Transchromosomic Cattle Neutralizes Multiple H1 Clades of Influenza A Virus by Recognizing a Novel Conformational Epitope in the Hemagglutinin Head Domain.
J Virol
; 94(22)2020 10 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-32847862
4.
Human Polyclonal Antibodies Produced by Transchromosomal Cattle Provide Partial Protection Against Lethal Zaire Ebolavirus Challenge in Rhesus Macaques.
J Infect Dis
; 218(suppl_5): S658-S661, 2018 11 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-30053153
5.
Fully Human Immunoglobulin G From Transchromosomic Bovines Treats Nonhuman Primates Infected With Ebola Virus Makona Isolate.
J Infect Dis
; 218(suppl_5): S636-S648, 2018 11 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-30010950
6.
Deployment of Transchromosomal Bovine for Personalized Antimicrobial Therapy.
Clin Infect Dis
; 66(7): 1116-1119, 2018 03 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-29272362
7.
Antibody Preparations from Human Transchromosomic Cows Exhibit Prophylactic and Therapeutic Efficacy against Venezuelan Equine Encephalitis Virus.
J Virol
; 91(14)2017 07 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28468884
8.
Sequential targeting of the genes encoding immunoglobulin-mu and prion protein in cattle.
Nat Genet
; 36(7): 775-80, 2004 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-15184897
9.
Transchromosomic bovine-derived anti-SARS-CoV-2 polyclonal human antibodies protects hACE2 transgenic hamsters against multiple variants.
iScience
; 26(10): 107764, 2023 Oct 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-37736038
10.
Polyclonal Antibodies Derived from Transchromosomic Bovines Vaccinated with the Recombinant F1-V Vaccine Increase Bacterial Opsonization In Vitro and Protect Mice from Pneumonic Plague.
Antibodies (Basel)
; 12(2)2023 May 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37218899
11.
Human immunoglobulin from transchromosomic bovines hyperimmunized with SARS-CoV-2 spike antigen efficiently neutralizes viral variants.
Hum Vaccin Immunother
; 18(2): 1940652, 2022 04 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-34228597
12.
Protection of human ACE2 transgenic Syrian hamsters from SARS CoV-2 variants by human polyclonal IgG from hyper-immunized transchromosomic bovines.
bioRxiv
; 2021 Jul 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-34341790
13.
Lipid Nanoparticle Formulation Increases Efficiency of DNA-Vectored Vaccines/Immunoprophylaxis in Animals Including Transchromosomic Bovines.
Sci Rep
; 10(1): 8764, 2020 05 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-32472093
14.
Anti-HFRS Human IgG Produced in Transchromosomic Bovines Has Potent Hantavirus Neutralizing Activity and Is Protective in Animal Models.
Front Microbiol
; 11: 832, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32508764
15.
Human Polyclonal Antibodies Produced from Transchromosomal Bovine Provides Prophylactic and Therapeutic Protections Against Zika Virus Infection in STAT2 KO Syrian Hamsters.
Viruses
; 11(2)2019 01 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-30678320
16.
Generation of H7N9-specific human polyclonal antibodies from a transchromosomic goat (caprine) system.
Sci Rep
; 9(1): 366, 2019 01 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-30675003
17.
Commercialising genetically engineered animal biomedical products.
Reprod Fertil Dev
; 20(1): 61-6, 2008.
Artículo
en Inglés
| MEDLINE | ID: mdl-18154699
18.
Safety and tolerability of a novel, polyclonal human anti-MERS coronavirus antibody produced from transchromosomic cattle: a phase 1 randomised, double-blind, single-dose-escalation study.
Lancet Infect Dis
; 18(4): 410-418, 2018 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29329957
19.
Cloned transchromosomic calves producing human immunoglobulin.
Nat Biotechnol
; 20(9): 889-94, 2002 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-12172556
20.
Clostridium difficile chimeric toxin receptor binding domain vaccine induced protection against different strains in active and passive challenge models.
Vaccine
; 35(33): 4079-4087, 2017 07 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-28669616