Detalles de la búsqueda
1.
Bioactivity-based analysis and chemical characterization of hypoglycemic and antioxidant components from Artemisia argyi.
Bioorg Chem
; 92: 103268, 2019 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-31541800
2.
The recent progress of isoxazole in medicinal chemistry.
Bioorg Med Chem
; 26(12): 3065-3075, 2018 07 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-29853341
3.
Chemical Constituents of the Seed Cake of Camellia oleifera and Their Antioxidant and Antimelanogenic Activities.
Chem Biodivers
; 15(7): e1800137, 2018 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-29763975
4.
Discovery and optimization of new benzofuran derivatives against p53-independent malignant cancer cells through inhibition of HIF-1 pathway.
Bioorg Med Chem Lett
; 26(11): 2713-8, 2016 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27101893
5.
Synthesis and evaluation of 4-(2-hydroxypropyl)piperazin-1-yl) derivatives as Hsp90 inhibitors.
Bioorg Med Chem
; 2016 Apr 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-27134115
6.
Discovery of new acetylcholinesterase inhibitors with small core structures through shape-based virtual screening.
Bioorg Med Chem Lett
; 25(17): 3442-6, 2015 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26212777
7.
Synthesis and evaluation of a novel class Hsp90 inhibitors containing 1-phenylpiperazine scaffold.
Bioorg Med Chem Lett
; 24(6): 1557-61, 2014 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24582477
8.
Investigation of the intermolecular recognition mechanism between the E3 ubiquitin ligase Keap1 and substrate based on multiple substrates analysis.
J Comput Aided Mol Des
; 28(12): 1233-45, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-25301376
9.
[Progress in research of the structural optimization of natural product-like Garcinia caged xanthones].
Yao Xue Xue Bao
; 49(3): 293-302, 2014 Mar.
Artículo
en Zh
| MEDLINE | ID: mdl-24961098
10.
Synthesis and antibacterial evaluation of a novel series of 10-hydroxyl ketolide derivatives.
Bioorg Med Chem Lett
; 23(11): 3452-7, 2013 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23591116
11.
Effective screening strategy using ensembled pharmacophore models combined with cascade docking: application to p53-MDM2 interaction inhibitors.
J Chem Inf Model
; 53(10): 2715-29, 2013 Oct 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-24050442
12.
Synthesis and evaluation of gambogic acid derivatives as antitumor agents. Part III.
Chem Biodivers
; 10(1): 73-85, 2013 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-23341209
13.
LYG-202 augments tumor necrosis factor-α-induced apoptosis via attenuating casein kinase 2-dependent nuclear factor-κB pathway in HepG2 cells.
Mol Pharmacol
; 82(5): 958-71, 2012 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-22909797
14.
Studies on chemical structure modification and structure-activity relationship of derivatives of gambogic acid at C(39).
Chem Biodivers
; 9(8): 1579-90, 2012 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-22899618
15.
Studies on chemical-structure modification and structure-activity relationship of gambogic acid derivatives at carbon(34).
Chem Biodivers
; 9(10): 2295-308, 2012 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-23081928
16.
Dual GSK-3ß/AChE Inhibitors as a New Strategy for Multitargeting Anti-Alzheimer's Disease Drug Discovery.
ACS Med Chem Lett
; 9(3): 171-176, 2018 Mar 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-29541355
17.
G9a - An Appealing Antineoplastic Target.
Curr Cancer Drug Targets
; 17(6): 555-568, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-27174055
18.
Discovery of novel inhibitors disrupting HIF-1α/von Hippel-Lindau interaction through shape-based screening and cascade docking.
PeerJ
; 4: e2757, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27994971
19.
CPUY201112, a novel synthetic small-molecule compound and inhibitor of heat shock protein Hsp90, induces p53-mediated apoptosis in MCF-7 cells.
Sci Rep
; 6: 19004, 2016 Jan 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-26743233
20.
Structure-based design and synthesis of small molecular inhibitors disturbing the interaction of MLL1-WDR5.
Eur J Med Chem
; 118: 1-8, 2016 Aug 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-27116709