Detalles de la búsqueda
1.
Biocatalytic reductive aminations with NAD(P)H-dependent enzymes: enzyme discovery, engineering and synthetic applications.
Chem Soc Rev
; 53(1): 227-262, 2024 Jan 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-38059509
2.
Engineering the Activity of a Newly Identified Arylalkylamine N-Acetyltransferase in the Acetylation of 5-Hydroxytryptamine.
Chembiochem
; 25(9): e202400069, 2024 May 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-38504591
3.
Engineering of a Baeyer-Villiger monooxygenase to improve substrate scope, stereoselectivity and regioselectivity.
Chembiochem
; : e202400328, 2024 May 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-38742991
4.
Chemoenzymatic Synthesis of Sterically Hindered Biaryls by Suzuki Coupling and Vanadium Chloroperoxidase Catalyzed Halogenations.
Chembiochem
; 24(1): e202200610, 2023 01 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36325954
5.
Whole-Cell Biotransformation of Penicillin G by a Three-Enzyme Co-expression System with Engineered Deacetoxycephalosporinâ C Synthase.
Chembiochem
; 23(11): e202200179, 2022 06 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-35384232
6.
Biosynthesis of ß-lactam nuclei in yeast.
Metab Eng
; 72: 56-65, 2022 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-35245651
7.
Biosynthesis of a rosavin natural product in Escherichia coli by glycosyltransferase rational design and artificial pathway construction.
Metab Eng
; 69: 15-25, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34715353
8.
Synthesis of Enantioenriched Sulfoxides by an Oxidation-Reduction Enzymatic Cascade.
Chemistry
; 28(61): e202201997, 2022 Nov 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-35938698
9.
Engineering of a thermophilic dihydroxy-acid dehydratase toward glycerate dehydration for in vitro biosystems.
Appl Microbiol Biotechnol
; 106(9-10): 3625-3637, 2022 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-35546366
10.
Tuning an Imine Reductase for the Asymmetric Synthesis of Azacycloalkylamines by Concise Structure-Guided Engineering.
Angew Chem Int Ed Engl
; 61(24): e202201908, 2022 06 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-35322515
11.
Unlocking the Stereoselectivity and Substrate Acceptance of Enzymes: Proline-Induced Loop Engineering Test.
Angew Chem Int Ed Engl
; 61(1): e202110793, 2022 01 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-34658118
12.
Utility of B-Factors in Protein Science: Interpreting Rigidity, Flexibility, and Internal Motion and Engineering Thermostability.
Chem Rev
; 119(3): 1626-1665, 2019 02 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-30698416
13.
Identification of Absidia orchidis steroid 11ß-hydroxylation system and its application in engineering Saccharomyces cerevisiae for one-step biotransformation to produce hydrocortisone.
Metab Eng
; 57: 31-42, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31669370
14.
The Crucial Role of Methodology Development in Directed Evolution of Selective Enzymes.
Angew Chem Int Ed Engl
; 59(32): 13204-13231, 2020 08 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-31267627
15.
Identification of a novel cytochrome P450 enzyme that catalyzes the C-2α hydroxylation of pentacyclic triterpenoids and its application in yeast cell factories.
Metab Eng
; 51: 70-78, 2019 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30339834
16.
Computational Insights into the Catalytic Mechanism of Bacterial Carboxylic Acid Reductase.
J Chem Inf Model
; 59(2): 832-841, 2019 02 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-30688451
17.
Structural and Computational Insight into the Catalytic Mechanism of Limonene Epoxide Hydrolase Mutants in Stereoselective Transformations.
J Am Chem Soc
; 140(1): 310-318, 2018 01 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-29232125
18.
Solid-Phase Gene Synthesis for Mutant Library Construction: The Future of Directed Evolution?
Chembiochem
; 19(19): 2023-2032, 2018 10 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30044530
19.
Clarifying the Difference between Iterative Saturation Mutagenesis as a Rational Guide in Directed Evolution and OmniChange as a Gene Mutagenesis Technique.
Chembiochem
; 19(24): 2542-2544, 2018 12 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-30408315
20.
Methodology Development in Directed Evolution: Exploring Options when Applying Triple-Code Saturation Mutagenesis.
Chembiochem
; 19(3): 239-246, 2018 02 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-29314451