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1.
Quantitative Imaging of Proteins in Tissue by Stable Isotope Labeled Mimetic Liquid Extraction Surface Analysis Mass Spectrometry.
Anal Chem
; 91(22): 14198-14202, 2019 11 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-31660728
2.
LESA MS Imaging of Heat-Preserved and Frozen Tissue: Benefits of Multistep Static FAIMS.
Anal Chem
; 90(22): 13306-13314, 2018 11 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-30350618
3.
Quantitation of Endogenous Metabolites in Mouse Tumors Using Mass-Spectrometry Imaging.
Anal Chem
; 90(10): 6051-6058, 2018 05 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29668267
4.
Mapping drug distribution in brain tissue using liquid extraction surface analysis mass spectrometry imaging.
Anal Chem
; 87(19): 10146-52, 2015 Oct 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-26350423
5.
Investigating nephrotoxicity of polymyxin derivatives by mapping renal distribution using mass spectrometry imaging.
Chem Res Toxicol
; 28(9): 1823-30, 2015 Sep 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-26293472
6.
Mass spectrometry imaging of cassette-dosed drugs for higher throughput pharmacokinetic and biodistribution analysis.
Anal Chem
; 86(16): 8473-80, 2014 Aug 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-25084360
7.
Targeted Desorption Electrospray Ionization Mass Spectrometry Imaging for Drug Distribution, Toxicity, and Tissue Classification Studies.
Metabolites
; 13(3)2023 Mar 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36984817
8.
Optimisation of pharmacokinetic properties in a neutral series of 11ß-HSD1 inhibitors.
Bioorg Med Chem Lett
; 22(21): 6756-61, 2012 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23013933
9.
Pharmacokinetics and metabolism of midazolam in chimeric mice with humanised livers.
Xenobiotica
; 42(11): 1128-37, 2012 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-22642803
10.
Correlating Mass Spectrometry Imaging and Liquid Chromatography-Tandem Mass Spectrometry for Tissue-Based Pharmacokinetic Studies.
Metabolites
; 12(3)2022 Mar 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-35323705
11.
Evaluation of Formalin-Fixed and FFPE Tissues for Spatially Resolved Metabolomics and Drug Distribution Studies.
Pharmaceuticals (Basel)
; 15(11)2022 Oct 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-36355479
12.
Correction: Brüning-Richardson et al. GSK-3 Inhibition Is Cytotoxic in Glioma Stem Cells through Centrosome Destabilization and Enhances the Effect of Radiotherapy in Orthotopic Models. Cancers 2021, 13, 5939.
Cancers (Basel)
; 14(15)2022 Aug 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-35954505
13.
GSK-3 Inhibition Is Cytotoxic in Glioma Stem Cells through Centrosome Destabilization and Enhances the Effect of Radiotherapy in Orthotopic Models.
Cancers (Basel)
; 13(23)2021 11 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-34885051
14.
Exemplifying the Screening Power of Mass Spectrometry Imaging over Label-Based Technologies for Simultaneous Monitoring of Drug and Metabolite Distributions in Tissue Sections.
J Biomol Screen
; 21(2): 187-93, 2016 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-26701101
15.
Spatial Quantitation of Drugs in tissues using Liquid Extraction Surface Analysis Mass Spectrometry Imaging.
Sci Rep
; 6: 37648, 2016 11 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-27883030
16.
Aurora kinase inhibitor nanoparticles target tumors with favorable therapeutic index in vivo.
Sci Transl Med
; 8(325): 325ra17, 2016 Feb 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-26865565
17.
Optimization of brain penetrant 11ß-hydroxysteroid dehydrogenase type I inhibitors and in vivo testing in diet-induced obese mice.
J Med Chem
; 57(3): 970-86, 2014 Feb 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-24422550
18.
11ß-Hydroxysteroid dehydrogenase type 1 (11ß-HSD1) inhibitors still improve metabolic phenotype in male 11ß-HSD1 knockout mice suggesting off-target mechanisms.
Endocrinology
; 154(12): 4580-93, 2013 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-24169553
19.
Determination of paracetamol in mouse, rat and dog plasma samples by laser diode thermal desorption--APCI-MS/MS.
Bioanalysis
; 4(11): 1327-35, 2012 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-22720651
20.
Novel acidic 11ß-hydroxysteroid dehydrogenase type 1 (11ß-HSD1) inhibitor with reduced acyl glucuronide liability: the discovery of 4-[4-(2-adamantylcarbamoyl)-5-tert-butyl-pyrazol-1-yl]benzoic acid (AZD8329).
J Med Chem
; 55(22): 10136-47, 2012 Nov 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-23088558