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1.
Chemoproteomic discovery of a covalent allosteric inhibitor of WRN helicase.
Nature
; 629(8011): 435-442, 2024 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-38658751
2.
DCAF11 Supports Targeted Protein Degradation by Electrophilic Proteolysis-Targeting Chimeras.
J Am Chem Soc
; 143(13): 5141-5149, 2021 04 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33783207
3.
Heteroaromatic-aminomethyl quinolones: potent and selective iNOS inhibitors.
Bioorg Med Chem Lett
; 22(2): 1237-41, 2012 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22182498
4.
Pharmacological characterization of KLYP961, a dual inhibitor of inducible and neuronal nitric-oxide synthases.
J Pharmacol Exp Ther
; 336(2): 468-78, 2011 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-21036913
5.
Identification and SAR of selective inducible nitric oxide synthase (iNOS) dimerization inhibitors.
Bioorg Med Chem Lett
; 21(22): 6888-94, 2011 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21986586
6.
KLYP956 is a non-imidazole-based orally active inhibitor of nitric-oxide synthase dimerization.
Mol Pharmacol
; 76(1): 153-62, 2009 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-19364813
7.
KD5170, a novel mercaptoketone-based histone deacetylase inhibitor that exhibits broad spectrum antitumor activity in vitro and in vivo.
Mol Cancer Ther
; 7(5): 1054-65, 2008 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-18483295
8.
Identification of KD5170: a novel mercaptoketone-based histone deacetylase inhibitor.
Bioorg Med Chem Lett
; 18(23): 6093-6, 2008 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18954983
9.
Alpha-mercaptoketone based histone deacetylase inhibitors.
Bioorg Med Chem Lett
; 18(24): 6482-5, 2008 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18954984
10.
Discovery of dual inducible/neuronal nitric oxide synthase (iNOS/nNOS) inhibitor development candidate 4-((2-cyclobutyl-1H-imidazo[4,5-b]pyrazin-1-yl)methyl)-7,8-difluoroquinolin-2(1H)-one (KD7332) part 2: identification of a novel, potent, and selective series of benzimidazole-quinolinone iNOS/nNOS dimerization inhibitors that are orally active in pain models.
J Med Chem
; 53(21): 7739-55, 2010 Nov 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-20931971
11.
Discovery of inducible nitric oxide synthase (iNOS) inhibitor development candidate KD7332, part 1: Identification of a novel, potent, and selective series of quinolinone iNOS dimerization inhibitors that are orally active in rodent pain models.
J Med Chem
; 52(9): 3047-62, 2009 May 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-19374401
12.
Inhibition of inducible nitric oxide synthase expression by a novel small molecule activator of the unfolded protein response.
Curr Chem Genomics
; 2: 1-9, 2008 Sep 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-20161838
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