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1.
In vitro reconstitution reveals a key role of human mitochondrial EXOG in RNA primer processing.
Nucleic Acids Res
; 50(14): 7991-8007, 2022 08 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-35819194
2.
Oxidative stress induces Z-DNA-binding protein 1-dependent activation of microglia via mtDNA released from retinal pigment epithelial cells.
J Biol Chem
; 298(1): 101523, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34953858
3.
Ligand-induced gene activation is associated with oxidative genome damage whose repair is required for transcription.
Proc Natl Acad Sci U S A
; 117(36): 22183-22192, 2020 09 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-32826329
4.
Early Inhibition of Fatty Acid Synthesis Reduces Generation of Memory Precursor Effector T Cells in Chronic Infection.
J Immunol
; 200(2): 643-656, 2018 01 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29237780
5.
The PARP inhibitor olaparib exerts beneficial effects in mice subjected to cecal ligature and puncture and in cells subjected to oxidative stress without impairing DNA integrity: A potential opportunity for repurposing a clinically used oncological drug for the experimental therapy of sepsis.
Pharmacol Res
; 145: 104263, 2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-31071432
6.
Suppression of Somatic Expansion Delays the Onset of Pathophysiology in a Mouse Model of Huntington's Disease.
PLoS Genet
; 11(8): e1005267, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-26247199
7.
Macrophages Promote Oxidative Metabolism To Drive Nitric Oxide Generation in Response to Trypanosoma cruzi.
Infect Immun
; 84(12): 3527-3541, 2016 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-27698021
8.
Cystathionine-beta-synthase inhibition for colon cancer: Enhancement of the efficacy of aminooxyacetic acid via the prodrug approach.
Mol Med
; 22: 361-379, 2016 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-27257787
9.
Screening of a composite library of clinically used drugs and well-characterized pharmacological compounds for cystathionine ß-synthase inhibition identifies benserazide as a drug potentially suitable for repurposing for the experimental therapy of colon cancer.
Pharmacol Res
; 113(Pt A): 18-37, 2016 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-27521834
10.
Opposing roles of mitochondrial and nuclear PARP1 in the regulation of mitochondrial and nuclear DNA integrity: implications for the regulation of mitochondrial function.
Nucleic Acids Res
; 42(21): 13161-73, 2014 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25378300
11.
Tumor-derived hydrogen sulfide, produced by cystathionine-ß-synthase, stimulates bioenergetics, cell proliferation, and angiogenesis in colon cancer.
Proc Natl Acad Sci U S A
; 110(30): 12474-9, 2013 Jul 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-23836652
12.
Upregulation and Mitochondrial Sequestration of Hemoglobin Occur in Circulating Leukocytes during Critical Illness, Conferring a Cytoprotective Phenotype.
Mol Med
; 21(1): 666-675, 2015 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-26322851
13.
Regulation of Vascular Tone, Angiogenesis and Cellular Bioenergetics by the 3-Mercaptopyruvate Sulfurtransferase/H2S Pathway: Functional Impairment by Hyperglycemia and Restoration by DL-α-Lipoic Acid.
Mol Med
; 21: 1-14, 2015 Feb 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-25715337
14.
Regulation of mitochondrial poly(ADP-Ribose) polymerase activation by the ß-adrenoceptor/cAMP/protein kinase A axis during oxidative stress.
Mol Pharmacol
; 86(4): 450-62, 2014 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-25069723
15.
Conserved structural chemistry for incision activity in structurally non-homologous apurinic/apyrimidinic endonuclease APE1 and endonuclease IV DNA repair enzymes.
J Biol Chem
; 288(12): 8445-8455, 2013 Mar 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-23355472
16.
Effect of S-adenosyl-L-methionine (SAM), an allosteric activator of cystathionine-ß-synthase (CBS) on colorectal cancer cell proliferation and bioenergetics in vitro.
Nitric Oxide
; 41: 146-56, 2014 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24667534
17.
AP39, a novel mitochondria-targeted hydrogen sulfide donor, stimulates cellular bioenergetics, exerts cytoprotective effects and protects against the loss of mitochondrial DNA integrity in oxidatively stressed endothelial cells in vitro.
Nitric Oxide
; 41: 120-30, 2014 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24755204
18.
Serum amyloid A and mitochondrial DNA in extracellular vesicles are novel markers for detecting traumatic brain injury in a mouse model.
iScience
; 27(2): 108932, 2024 Feb 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-38323004
19.
Role of human DNA glycosylase Nei-like 2 (NEIL2) and single strand break repair protein polynucleotide kinase 3'-phosphatase in maintenance of mitochondrial genome.
J Biol Chem
; 287(4): 2819-29, 2012 Jan 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-22130663
20.
Non-Invasive Evaluation of Retinal Vascular Alterations in a Mouse Model of Optic Neuritis Using Laser Speckle Flowgraphy and Optical Coherence Tomography Angiography.
Cells
; 12(23)2023 11 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-38067113