Detalles de la búsqueda
1.
Physiologically-based pharmacokinetic modeling for mirabegron: a multi-elimination pathway mediated by cytochrome P450 3A4, uridine 5'-diphosphate-glucuronosyltransferase 2B7, and butyrylcholinesterase.
Xenobiotica
; 49(8): 912-921, 2019 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-30301385
2.
Application of a physiologically based pharmacokinetic model for the prediction of mirabegron plasma concentrations in a population with severe renal impairment.
Biopharm Drug Dispos
; 40(5-6): 176-187, 2019 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-30985942
3.
Transcriptome analysis of a Pseudomonas aeruginosasn-glycerol-3-phosphate dehydrogenase mutant reveals a disruption in bioenergetics.
Microbiology (Reading)
; 164(4): 551-562, 2018 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29533746
4.
Quantitative LC/ESI-SRM/MS of antibody biopharmaceuticals: use of a homologous antibody as an internal standard and three-step method development.
Anal Bioanal Chem
; 409(23): 5523-5532, 2017 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-28710515
5.
Comparison of intestinal metabolism of CYP3A substrates between rats and humans: application of portal-systemic concentration difference method.
Xenobiotica
; 44(6): 511-21, 2014 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-24329478
6.
Species differences in intestinal glucuronidation activities between humans, rats, dogs and monkeys.
Xenobiotica
; 44(3): 205-16, 2014 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-23962030
7.
Measurement of soil bacterial colony temperatures and isolation of a high heat-producing bacterium.
BMC Microbiol
; 13: 56, 2013 Mar 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-23497132
8.
Synergistic antitumor activities of sepantronium bromide (YM155), a survivin suppressant, in combination with microtubule-targeting agents in triple-negative breast cancer cells.
Biol Pharm Bull
; 36(12): 1921-7, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-24432379
9.
A comparison of pharmacokinetics between humans and monkeys.
Drug Metab Dispos
; 38(2): 308-16, 2010 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-19910513
10.
Quantitative prediction of intestinal metabolism in humans from a simplified intestinal availability model and empirical scaling factor.
Drug Metab Dispos
; 38(7): 1230-7, 2010 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-20354105
11.
Exploratory population pharmacokinetics (e-PPK) analysis for predicting human PK using exploratory ADME data during early drug discovery research.
Eur J Drug Metab Pharmacokinet
; 34(2): 117-28, 2009.
Artículo
en Inglés
| MEDLINE | ID: mdl-19645221
12.
[An introduction to QSP modeling for pharmacologists].
Nihon Yakurigaku Zasshi
; 154(3): 143-150, 2019.
Artículo
en Japonés
| MEDLINE | ID: mdl-31527365
13.
The Impact of Endogenous Breast Cancer Resistance Protein on Human P-Glycoprotein-Mediated Transport Assays Using LLC-PK1 Cells Transfected With Human P-Glycoprotein.
J Pharm Sci
; 108(3): 1085-1089, 2019 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-30339864
14.
Possible involvement of the µ opioid receptor in the antinociception induced by sinomenine on formalin-induced nociceptive behavior in mice.
Neurosci Lett
; 699: 103-108, 2019 04 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-30690119
15.
Recent Progress in Hepatocyte Culture Models and Their Application to the Assessment of Drug Metabolism, Transport, and Toxicity in Drug Discovery: The Value of Tissue Engineering for the Successful Development of a Microphysiological System.
J Pharm Sci
; 106(9): 2302-2311, 2017 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-28533121
16.
Population pharmacokinetic analysis of micafungin in Japanese patients with fungal infections.
Drug Metab Pharmacokinet
; 21(4): 324-31, 2006 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-16946560
17.
Pharmacokinetics-pharmacodynamics of micafungin in Japanese patients with deep-seated mycosis.
Eur J Drug Metab Pharmacokinet
; 31(2): 123-8, 2006.
Artículo
en Inglés
| MEDLINE | ID: mdl-16898081
18.
[Development of new software (Ver. 2.0) based on the Bayesian estimation utilized in the therapeutic drug monitoring of teicoplanin, a glycopeptide antibiotic].
Jpn J Antibiot
; 59(3): 165-76, 2006 Jun.
Artículo
en Japonés
| MEDLINE | ID: mdl-16913403
19.
Prediction of hepatic and intestinal glucuronidation using in vitro-in vivo extrapolation.
Drug Metab Pharmacokinet
; 30(1): 21-9, 2015 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-25760528
20.
Development and validation of semiautomated 96-well transport assay using LLC-PK1 cells transfected with human P-glycoprotein for high-throughput screening.
Assay Drug Dev Technol
; 13(2): 79-87, 2015 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-25785771