Detalles de la búsqueda
1.
The A3 adenosine receptor: history and perspectives.
Pharmacol Rev
; 67(1): 74-102, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25387804
2.
Antidyskinetic effect of A2A and 5HT1A/1B receptor ligands in two animal models of Parkinson's disease.
Mov Disord
; 31(4): 501-11, 2016 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-26871939
3.
Synthesis and biological evaluation of novel 2-amino-3-aroyl-4-neopentyl-5-substituted thiophene derivatives as allosteric enhancers of the A1 adenosine receptor.
Bioorg Med Chem
; 22(1): 148-66, 2014 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24332652
4.
Design, synthesis and biological evaluation of 3,5-disubstituted 2-amino thiophene derivatives as a novel class of antitumor agents.
Bioorg Med Chem
; 22(18): 5097-109, 2014 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24398384
5.
Synthesis and biological evaluation of 2-substituted-4-(3',4',5'-trimethoxyphenyl)-5-aryl thiazoles as anticancer agents.
Bioorg Med Chem
; 20(24): 7083-94, 2012 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23117171
6.
Structure-activity relationships of 2-amino-3-aroyl-4-[(4-arylpiperazin-1-yl)methyl]thiophenes. Part 2: Probing the influence of diverse substituents at the phenyl of the arylpiperazine moiety on allosteric enhancer activity at the A1 adenosine receptor.
Bioorg Med Chem
; 20(2): 996-1007, 2012 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22182575
7.
Recent developments in A2B adenosine receptor ligands.
Handb Exp Pharmacol
; (193): 99-122, 2009.
Artículo
en Inglés
| MEDLINE | ID: mdl-19639280
8.
Discovery of 8-methoxypyrazino[1,2-a]indole as a New Potent Antiproliferative Agent Against Human Leukemia K562 Cells. A Structure-Activity Relationship Study.
Lett Drug Des Discov
; 6(4): 298-303, 2009 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20161090
9.
Synthesis and biological evaluation of 1-methyl-2-(3',4',5'-trimethoxybenzoyl)-3-aminoindoles as a new class of antimitotic agents and tubulin inhibitors.
J Med Chem
; 51(5): 1464-8, 2008 Mar 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-18260616
10.
1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A(2B) adenosine receptor antagonists.
Bioorg Med Chem
; 16(5): 2419-30, 2008 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18077171
11.
Structure-activity relationship studies of a new series of imidazo[2,1-f]purinones as potent and selective A(3) adenosine receptor antagonists.
Bioorg Med Chem
; 16(24): 10281-94, 2008 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19006671
12.
Synthesis and biological evaluation of novel 1-deoxy-1-[6-[((hetero)arylcarbonyl)hydrazino]- 9H-purin-9-yl]-N-ethyl-beta-D-ribofuranuronamide derivatives as useful templates for the development of A2B adenosine receptor agonists.
J Med Chem
; 50(2): 374-80, 2007 Jan 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-17228880
13.
From tyrosine to glycine: synthesis and biological activity of potent antagonists of the purinergic P2X7 receptor.
J Med Chem
; 50(15): 3706-15, 2007 Jul 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-17585854
14.
Synthesis and biological evaluation of 2- and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization.
J Med Chem
; 50(9): 2273-7, 2007 May 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-17419607
15.
Synthesis and biological evaluation of 2-amino-3-(3', 4', 5'-trimethoxy-phenylsulfonyl)-5-aryl thiophenes as a new class of antitubulin agents.
Med Chem
; 3(6): 507-12, 2007 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-18045199
16.
Ligands for A2B adenosine receptor subtype.
Curr Med Chem
; 13(28): 3467-82, 2006.
Artículo
en Inglés
| MEDLINE | ID: mdl-17168717
17.
Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxybenzoyl)-5-aryl thiophenes as a new class of potent antitubulin agents.
J Med Chem
; 49(13): 3906-15, 2006 Jun 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-16789746
18.
Synthesis and biological evaluation of 2-(3',4',5'-trimethoxybenzoyl)-3-amino 5-aryl thiophenes as a new class of tubulin inhibitors.
J Med Chem
; 49(21): 6425-8, 2006 Oct 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-17034150
19.
Dopamine and adenosine receptor interaction as basis for the treatment of Parkinson's disease.
J Neurol Sci
; 248(1-2): 48-52, 2006 Oct 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-16780890
20.
Design and Synthesis of Potent in Vitro and in Vivo Anticancer Agents Based on 1-(3',4',5'-Trimethoxyphenyl)-2-Aryl-1H-Imidazole.
Sci Rep
; 6: 26602, 2016 05 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-27216165