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1.
Tristetraprolin Recruits the Herpes Simplex Virion Host Shutoff RNase to AU-Rich Elements in Stress Response mRNAs To Enable Their Cleavage.
J Virol
; 89(10): 5643-50, 2015 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-25762736
2.
Selective degradation of mRNAs by the HSV host shutoff RNase is regulated by the UL47 tegument protein.
Proc Natl Acad Sci U S A
; 110(18): E1669-75, 2013 Apr 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-23589852
3.
The herpes simplex virus host shutoff RNase degrades cellular and viral mRNAs made before infection but not viral mRNA made after infection.
J Virol
; 87(8): 4516-22, 2013 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-23388723
4.
The nuclear-cytoplasmic shuttling of virion host shutoff RNase is enabled by pUL47 and an embedded nuclear export signal and defines the sites of degradation of AU-rich and stable cellular mRNAs.
J Virol
; 87(24): 13569-78, 2013 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-24109211
5.
The virion host shutoff RNase plays a key role in blocking the activation of protein kinase R in cells infected with herpes simplex virus 1.
J Virol
; 87(6): 3271-6, 2013 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-23302873
6.
The virion-packaged endoribonuclease of herpes simplex virus 1 cleaves mRNA in polyribosomes.
Proc Natl Acad Sci U S A
; 106(29): 12139-44, 2009 Jul 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-19584246
7.
Role of herpes simplex virus ICP27 in the degradation of mRNA by virion host shutoff RNase.
J Virol
; 84(19): 10182-90, 2010 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-20631134
8.
Fibroblast Growth Factor-2 and the HIV-1 Tat Protein Synergize in Promoting Bcl-2 Expression and Preventing Endothelial Cell Apoptosis: Implications for the Pathogenesis of AIDS-Associated Kaposi's Sarcoma.
Int J Vasc Med
; 2011: 452729, 2011.
Artículo
en Inglés
| MEDLINE | ID: mdl-22007303
9.
Interaction of herpes simplex virus RNase with VP16 and VP22 is required for the accumulation of the protein but not for accumulation of mRNA.
Proc Natl Acad Sci U S A
; 104(29): 12163-8, 2007 Jul 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-17620619
10.
Replication-competent herpes simplex virus 1 isolates selected from cells transfected with a bacterial artificial chromosome DNA lacking only the UL49 gene vary with respect to the defect in the UL41 gene encoding host shutoff RNase.
J Virol
; 81(20): 10924-32, 2007 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-17670820
11.
The virion host shutoff protein (UL41) of herpes simplex virus 1 is an endoribonuclease with a substrate specificity similar to that of RNase A.
J Virol
; 80(18): 9341-5, 2006 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-16940547
12.
The U(L)41 protein of herpes simplex virus 1 degrades RNA by endonucleolytic cleavage in absence of other cellular or viral proteins.
Proc Natl Acad Sci U S A
; 103(8): 2827-32, 2006 Feb 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-16477041
13.
The UL41 protein of herpes simplex virus mediates selective stabilization or degradation of cellular mRNAs.
Proc Natl Acad Sci U S A
; 101(52): 18165-70, 2004 Dec 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-15596716
14.
Herpes simplex virus 1 induces cytoplasmic accumulation of TIA-1/TIAR and both synthesis and cytoplasmic accumulation of tristetraprolin, two cellular proteins that bind and destabilize AU-rich RNAs.
J Virol
; 78(16): 8582-92, 2004 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-15280467
15.
The patterns of accumulation of cellular RNAs in cells infected with a wild-type and a mutant herpes simplex virus 1 lacking the virion host shutoff gene.
Proc Natl Acad Sci U S A
; 99(26): 17031-6, 2002 Dec 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-12481033
16.
Activation of NF-kappaB in cells productively infected with HSV-1 depends on activated protein kinase R and plays no apparent role in blocking apoptosis.
Proc Natl Acad Sci U S A
; 100(21): 12408-13, 2003 Oct 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-14530405
17.
The herpes simplex virus 1 UL41 gene-dependent destabilization of cellular RNAs is selective and may be sequence-specific.
Proc Natl Acad Sci U S A
; 101(10): 3603-8, 2004 Mar 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-14993598
18.
Cells lacking NF-kappaB or in which NF-kappaB is not activated vary with respect to ability to sustain herpes simplex virus 1 replication and are not susceptible to apoptosis induced by a replication-incompetent mutant virus.
J Virol
; 78(21): 11615-21, 2004 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-15479802
19.
The stress-inducible immediate-early responsive gene IEX-1 is activated in cells infected with herpes simplex virus 1, but several viral mechanisms, including 3' degradation of its RNA, preclude expression of the gene.
J Virol
; 77(11): 6178-87, 2003 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-12743274
20.
Of the three tegument proteins that package mRNA in herpes simplex virions, one (VP22) transports the mRNA to uninfected cells for expression prior to viral infection.
Proc Natl Acad Sci U S A
; 99(12): 8318-23, 2002 Jun 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-12060774
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