Detalles de la búsqueda
1.
Design, synthesis and molecular docking of new [1,2,4] triazolo[4,3-a]quinoxaline derivatives as anticancer agents targeting VEGFR-2 kinase.
Mol Divers
; 26(4): 1915-1932, 2022 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-34460053
2.
Design and synthesis of thiazolidine-2,4-diones hybrids with 1,2-dihydroquinolones and 2-oxindoles as potential VEGFR-2 inhibitors: in-vitro anticancer evaluation and in-silico studies.
J Enzyme Inhib Med Chem
; 37(1): 1903-1917, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-35801403
3.
New benzoxazole derivatives as potential VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, anti-proliferative evaluation, flowcytometric analysis, and in silico studies.
J Enzyme Inhib Med Chem
; 37(1): 397-410, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-34961427
4.
Benzoxazole derivatives as new VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, in silico studies, and antiproliferative evaluation.
J Enzyme Inhib Med Chem
; 37(1): 2063-2077, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-35875937
5.
Discovery of 2,4-thiazolidinedione-tethered coumarins as novel selective inhibitors for carbonic anhydrase IX and XII isoforms.
J Enzyme Inhib Med Chem
; 37(1): 531-541, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-34991416
6.
New quinoline and isatin derivatives as apoptotic VEGFR-2 inhibitors: design, synthesis, anti-proliferative activity, docking, ADMET, toxicity, and MD simulation studies.
J Enzyme Inhib Med Chem
; 37(1): 2191-2205, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-35975321
7.
Targeting VEGFR-2 by new quinoxaline derivatives: Design, synthesis, antiproliferative assay, apoptosis induction, and in silico studies.
Arch Pharm (Weinheim)
; 355(2): e2100359, 2022 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-34862634
8.
Modified Benzoxazole-Based VEGFR-2 Inhibitors and Apoptosis Inducers: Design, Synthesis, and Anti-Proliferative Evaluation.
Molecules
; 27(15)2022 Aug 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-35956997
9.
Identification of new [1,2,4]triazolo[4,3-a]quinoxalines as potent VEGFR-2 tyrosine kinase inhibitors: Design, synthesis, anticancer evaluation, and in silico studies.
Bioorg Med Chem
; 46: 116384, 2021 09 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-34479065
10.
Discovery of new VEGFR-2 inhibitors based on bis([1, 2, 4]triazolo)[4,3-a:3',4'-c]quinoxaline derivatives as anticancer agents and apoptosis inducers.
J Enzyme Inhib Med Chem
; 36(1): 1093-1114, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-34056992
11.
Discovery of new 3-methylquinoxalines as potential anti-cancer agents and apoptosis inducers targeting VEGFR-2: design, synthesis, and in silico studies.
J Enzyme Inhib Med Chem
; 36(1): 1732-1750, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-34325596
12.
Design and discovery of new 1,2,4-triazolo[4,3-c]quinazolines as potential DNA intercalators and topoisomerase II inhibitors.
Arch Pharm (Weinheim)
; 354(3): e2000237, 2021 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-33226150
13.
In Silico Studies of Some Isoflavonoids as Potential Candidates against COVID-19 Targeting Human ACE2 (hACE2) and Viral Main Protease (Mpro).
Molecules
; 26(9)2021 May 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34068579
14.
Discovery of new pyrimidine-5-carbonitrile derivatives as anticancer agents targeting EGFRWT and EGFRT790M.
Org Biomol Chem
; 18(38): 7608-7634, 2020 10 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32959865
15.
Discovery and antiproliferative evaluation of new quinoxalines as potential DNA intercalators and topoisomerase II inhibitors.
Arch Pharm (Weinheim)
; 352(11): e1900123, 2019 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-31463953
16.
Discovery of new thiazolidine-2,4-dione derivatives as potential VEGFR-2 inhibitors: In vitro and in silico studies.
Heliyon
; 10(2): e24005, 2024 Jan 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-38298627
17.
New thiazolidine-2,4-diones as potential anticancer agents and apoptotic inducers targeting VEGFR-2 kinase: Design, synthesis, in silico and in vitro studies.
Biochim Biophys Acta Gen Subj
; 1868(6): 130599, 2024 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-38521471
18.
Design, synthesis, anticancer evaluation, and in silico ADMET analysis of novel thalidomide analogs as promising immunomodulatory agents.
RSC Adv
; 13(16): 10488-10502, 2023 Apr 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-37021105
19.
In vitro and in silico evaluation of new thieno[2,3-d]pyrimidines as anti-cancer agents and apoptosis inducers targeting VEGFR-2.
Comput Biol Chem
; 106: 107928, 2023 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-37480629
20.
New theobromine derivatives inhibiting VEGFR-2: design, synthesis, antiproliferative, docking and molecular dynamics simulations.
Future Med Chem
; 15(14): 1233-1250, 2023 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-37466069