Detalles de la búsqueda
1.
Discovery of novel octahydroquinazoline scaffolds endowed with dual inhibition of tubulin polymerization/Eg5 against HCC: Apoptotic and radio-chemotherapeutic studies.
Bioorg Chem
; 148: 107449, 2024 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-38759356
2.
Tailored quinoline hybrids as promising COX-2/15-LOX dual inhibitors endowed with diverse safety profile: Design, synthesis, SAR, and histopathological study.
Bioorg Chem
; 145: 107244, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-38428284
3.
Effect of autologous platelet-rich plasma on the fertility and quality of cryopreserved buffalo bull semen: a comparative study using OptiXcell® and tris egg yolk extenders.
BMC Vet Res
; 20(1): 250, 2024 Jun 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-38849855
4.
Schiff bases as linker in the development of quinoline-sulfonamide hybrids as selective cancer-associated carbonic anhydrase isoforms IX/XII inhibitors: A new regioisomerism tactic.
Bioorg Chem
; 131: 106309, 2023 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-36502567
5.
Design and synthesis of uracil/thiouracil based quinoline scaffolds as topoisomerases I/II inhibitors for chemotherapy: A new hybrid navigator with DFT calculation.
Bioorg Chem
; 136: 106560, 2023 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-37121108
6.
New pyrimidine/thiazole hybrids endowed with analgesic, anti-inflammatory, and lower cardiotoxic activities: Design, synthesis, and COX-2/sEH dual inhibition.
Arch Pharm (Weinheim)
; 355(7): e2200024, 2022 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-35429006
7.
Synthesis, Antimicrobial, Anti-Virulence and Anticancer Evaluation of New 5(4H)-Oxazolone-Based Sulfonamides.
Molecules
; 27(3)2022 Jan 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-35163939
8.
Design, synthesis, biological evaluation, and computational studies of novel thiazolo-pyrazole hybrids as promising selective COX-2 inhibitors: Implementation of apoptotic genes expression for ulcerogenic liability assessment.
Bioorg Chem
; 111: 104883, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33865053
9.
Design, synthesis, and biological evaluation of new pyrimidine-5-carbonitrile derivatives bearing 1,3-thiazole moiety as novel anti-inflammatory EGFR inhibitors with cardiac safety profile.
Bioorg Chem
; 111: 104890, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33872924
10.
Discovery of novel quinoline-based analogues of combretastatin A-4 as tubulin polymerisation inhibitors with apoptosis inducing activity and potent anticancer effect.
J Enzyme Inhib Med Chem
; 36(1): 802-818, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-33730937
11.
Design, Synthesis, Biological Evaluation, and Computational Studies of Novel Tri-Aryl Imidazole-Benzene Sulfonamide Hybrids as Promising Selective Carbonic Anhydrase IX and XII Inhibitors.
Molecules
; 26(16)2021 Aug 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-34443307
12.
Design and synthesis of novel pyrazolo[3,4-d]pyrimidin-4-one bearing quinoline scaffold as potent dual PDE5 inhibitors and apoptotic inducers for cancer therapy.
Bioorg Chem
; 105: 104352, 2020 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33080494
13.
Design, synthesis and biological evaluation of novel 5-((substituted quinolin-3-yl/1-naphthyl) methylene)-3-substituted imidazolidin-2,4-dione as HIV-1 fusion inhibitors.
Bioorg Chem
; 99: 103782, 2020 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32229348
14.
In Vitro Antimycobacterial Activity and Physicochemical Characterization of Diaryl Ether Triclosan Analogues as Potential InhA Reductase Inhibitors.
Molecules
; 25(14)2020 Jul 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-32650556
15.
The Exploitation of Enzymatically-Derived cis-1,2-Dihydrocatechols and Related Compounds in the Synthesis of Biologically Active Natural Products.
Chem Rec
; 18(2): 239-264, 2018 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-29205772
16.
The Synthesis of Certain Derivatives and Analogues of (-)- and (+)-Galanthamine and an Assessment of their Capacities to Inhibit Acetylcholine Esterase.
J Org Chem
; 82(15): 7869-7886, 2017 08 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-28671462
17.
The Synthesis of Certain Phomentrioloxin A Analogues and Their Evaluation as Herbicidal Agents.
J Org Chem
; 82(1): 211-233, 2017 01 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-28026176
18.
Chemoenzymatic Synthesis of (+)-Asperpentyn and the Enantiomer of the Structure Assigned to Aspergillusol A.
J Nat Prod
; 78(8): 1963-8, 2015 Aug 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-26270650
19.
The potential biological activities of Aspergillus luchuensis-aided green synthesis of silver nanoparticles.
Front Microbiol
; 15: 1381302, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-38832112
20.
Tailored Tetrasubstituted Imidazole Carrying the Benzenesulfonamide Fragments as Selective Human Carbonic Anhydrase IX/XII Inhibitors.
ChemMedChem
; 19(10): e202400004, 2024 May 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-38356418