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1.
Discovery of highly potent and selective biphenylacylsulfonamide-based beta3-adrenergic receptor agonists and molecular modeling based on the solved X-ray structure of the beta2-adrenergic receptor: part 6.
Bioorg Med Chem Lett
; 19(16): 4679-83, 2009 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19608416
2.
Discovery of a novel series of biphenyl benzoic acid derivatives as potent and selective human beta3-adrenergic receptor agonists with good oral bioavailability. Part I.
J Med Chem
; 51(6): 1925-44, 2008 Mar 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-18307290
3.
Immunosuppressive effect of ASP2408, a novel CD86-selective variant of CTLA4-Ig, in rats and cynomolgus monkeys.
Int Immunopharmacol
; 40: 310-317, 2016 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-27662596
4.
The Effect of ASP2409, a Novel CD86-Selective Variant of CTLA4-Ig, on Renal Allograft Rejection in Nonhuman Primates.
Transplantation
; 100(12): 2611-2620, 2016 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-27861289
5.
Correlation of intrinsic in vitro and in vivo clearance for drugs metabolized by hepatic UDP-glucuronosyltransferases in rats.
Drug Metab Pharmacokinet
; 26(5): 465-73, 2011.
Artículo
en Inglés
| MEDLINE | ID: mdl-21727754
6.
Discovery of highly potent and selective biphenylacylsulfonamide-based beta3-adrenergic receptor agonists and evaluation of physical properties as potential overactive bladder therapies: part 5.
J Med Chem
; 52(9): 3063-72, 2009 May 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-19366244
7.
Discovery of a novel series of benzoic acid derivatives as potent and selective human beta3 adrenergic receptor agonists with good oral bioavailability. 3. Phenylethanolaminotetraline (PEAT) skeleton containing biphenyl or biphenyl ether moiety.
J Med Chem
; 51(15): 4804-22, 2008 Aug 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-18651730
8.
Discovery of a novel series of biphenyl benzoic acid derivatives as highly potent and selective human beta3 adrenergic receptor agonists with good oral bioavailability. Part II.
J Med Chem
; 51(13): 4002-20, 2008 Jul 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-18553954
9.
Metabolism investigation leading to novel drug design 2: orally active prostacyclin mimetics. Part 5.
Bioorg Med Chem Lett
; 16(17): 4475-8, 2006 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-16824754
10.
Metabolism investigation leading to novel drug design: orally active prostacyclin mimetics. Part 4.
Bioorg Med Chem Lett
; 15(13): 3284-7, 2005 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-15935659
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