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1.
Antiobesity and emetic effects of a short-length peptide YY analog and its PEGylated and alkylated derivatives.
Bioorg Med Chem
; 26(3): 566-572, 2018 02 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29279243
2.
A potent neuromedin U receptor 2-selective alkylated peptide.
Bioorg Med Chem Lett
; 27(20): 4626-4629, 2017 10 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28935264
3.
A potent and selective natriuretic peptide receptor-3 blocker 11-mer peptide created by hybridization of musclin and atrial natriuretic peptide.
Bioorg Med Chem Lett
; 27(15): 3542-3545, 2017 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28596054
4.
Potent antiobesity effect of a short-length peptide YY-analogue continuously administered in mice.
Bioorg Med Chem Lett
; 27(16): 3829-3832, 2017 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28684122
5.
A PEGylated analog of short-length Neuromedin U with potent anorectic and anti-obesity effects.
Bioorg Med Chem
; 25(8): 2307-2312, 2017 04 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28291683
6.
Highly potent antiobesity effect of a short-length peptide YY analog in mice.
Bioorg Med Chem
; 25(20): 5718-5725, 2017 10 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28917449
7.
Discovery of an artificial peptide agonist to the fibroblast growth factor receptor 1c/ßKlotho complex from random peptide T7 phage display.
Biochem Biophys Res Commun
; 480(1): 55-60, 2016 Nov 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-27717820
8.
Optimization of a novel series of N-phenylindoline-5-sulfonamide-based acyl CoA:monoacylglycerol acyltransferase-2 inhibitors: Mitigation of CYP3A4 time-dependent inhibition and phototoxic liabilities.
Bioorg Med Chem
; 23(15): 4544-4560, 2015 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26100443
9.
Design and biological evaluation of imidazo[1,2-a]pyridines as novel and potent ASK1 inhibitors.
Bioorg Med Chem Lett
; 22(24): 7326-9, 2012 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23147077
10.
Versatile live-attenuated SARS-CoV-2 vaccine platform applicable to variants induces protective immunity.
iScience
; 25(11): 105412, 2022 Nov 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-36320329
11.
Melanin-concentrating hormone receptor 1 antagonists: synthesis, structure-activity relationship, docking studies, and biological evaluation of 2,3,4,5-tetrahydro-1H-3-benzazepine derivatives.
Bioorg Med Chem
; 19(21): 6261-73, 2011 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21975069
12.
Discovery, synthesis, and structure-activity relationship of 6-aminomethyl-7,8-dihydronaphthalenes as human melanin-concentrating hormone receptor 1 antagonists.
Bioorg Med Chem
; 19(18): 5539-52, 2011 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21856163
13.
Inhibition of MGAT2 modulates fat-induced gut peptide release and fat intake in normal mice and ameliorates obesity and diabetes in ob/ob mice fed on a high-fat diet.
FEBS Open Bio
; 10(3): 316-326, 2020 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-31837122
14.
Identification and Characterization of a New Series of Ghrelin O-Acyl Transferase Inhibitors.
SLAS Discov
; 23(2): 154-163, 2018 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-28846466
15.
Differential effects of selective agonists of neuromedin U1 and U2 receptors in obese and diabetic mice.
Br J Pharmacol
; 175(2): 359-373, 2018 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29057457
16.
A novel and selective melanin-concentrating hormone receptor 1 antagonist ameliorates obesity and hepatic steatosis in diet-induced obese rodent models.
Eur J Pharmacol
; 796: 45-53, 2017 Feb 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-27986627
17.
Potent Body Weight-Lowering Effect of a Neuromedin U Receptor 2-selective PEGylated Peptide.
J Med Chem
; 60(14): 6089-6097, 2017 07 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-28657315
18.
Pharmacological Inhibition of Monoacylglycerol O-Acyltransferase 2 Improves Hyperlipidemia, Obesity, and Diabetes by Change in Intestinal Fat Utilization.
PLoS One
; 11(3): e0150976, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-26938273
19.
Discovery of a Novel Series of N-Phenylindoline-5-sulfonamide Derivatives as Potent, Selective, and Orally Bioavailable Acyl CoA:Monoacylglycerol Acyltransferase-2 Inhibitors.
J Med Chem
; 58(9): 3892-909, 2015 May 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-25897973
20.
T-226296: a novel, orally active and selective melanin-concentrating hormone receptor antagonist.
Eur J Pharmacol
; 438(3): 129-35, 2002 Mar 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-11909603