Detalles de la búsqueda
1.
Phase 1 study on the safety and efficacy of E6011, antifractalkine antibody, in patients with Crohn's disease.
J Gastroenterol Hepatol
; 36(8): 2180-2186, 2021 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-33599356
2.
Investigation of Fluorescein Derivatives as Substrates of Organic Anion Transporting Polypeptide (OATP) 1B1 To Develop Sensitive Fluorescence-Based OATP1B1 Inhibition Assays.
Mol Pharm
; 13(2): 438-48, 2016 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26696140
3.
Investigation of the impact of substrate selection on in vitro organic anion transporting polypeptide 1B1 inhibition profiles for the prediction of drug-drug interactions.
Drug Metab Dispos
; 43(2): 235-47, 2015 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-25414411
4.
HPLC with fluorescence detection assay of perampanel, a novel AMPA receptor antagonist, in human plasma for clinical pharmacokinetic studies.
Biomed Chromatogr
; 29(10): 1589-93, 2015 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-25828925
5.
Design, synthesis, and structure-activity relationships of a series of novel N-aryl-2-phenylcyclopropanecarboxamide that are potent and orally active orexin receptor antagonists.
Bioorg Med Chem
; 22(21): 6071-88, 2014 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25267004
6.
Population pharmacokinetic-pharmacodynamic modeling of serum biomarkers as predictors of tumor dynamics following lenvatinib treatment in patients with radioiodine-refractory differentiated thyroid cancer (RR-DTC).
CPT Pharmacometrics Syst Pharmacol
; 13(6): 954-969, 2024 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-38528813
7.
Species difference in the mechanism of nonlinear pharmacokinetics of E2074, a novel sodium channel inhibitor, in rats, dogs, and monkeys.
Drug Metab Dispos
; 41(5): 1004-11, 2013 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-23401471
8.
Substrate-dependent inhibition of organic anion transporting polypeptide 1B1: comparative analysis with prototypical probe substrates estradiol-17ß-glucuronide, estrone-3-sulfate, and sulfobromophthalein.
Drug Metab Dispos
; 41(10): 1859-66, 2013 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-23920221
9.
Population pharmacokinetic-pharmacodynamic analyses of amyloid positron emission tomography and plasma biomarkers for lecanemab in subjects with early Alzheimer's disease.
CPT Pharmacometrics Syst Pharmacol
; 11(12): 1578-1591, 2022 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-36165093
10.
Perampanel: a novel, orally active, noncompetitive AMPA-receptor antagonist that reduces seizure activity in rodent models of epilepsy.
Epilepsia
; 52(7): 1331-40, 2011 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-21635236
11.
Lineage-specific duplication and loss of pepsinogen genes in hominoid evolution.
J Mol Evol
; 70(4): 313-24, 2010 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-20349055
12.
Relic of ancient recombinations in gibbon ABO blood group genes deciphered through phylogenetic network analysis.
Mol Phylogenet Evol
; 51(3): 465-71, 2009 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-19298858
13.
Relatedness in wild chimpanzees: influence of paternity, male philopatry, and demographic factors.
Am J Phys Anthropol
; 137(3): 256-62, 2008 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-18512686
14.
Wild chimpanzee infant urine and saliva sampled noninvasively usable for DNA analyses.
Primates
; 48(2): 156-9, 2007 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-17111091
15.
Comparative analysis of estrogen receptor gene polymorphisms in apes.
Primates
; 48(2): 151-5, 2007 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-17024513
16.
Comparison of the Predictability of Human Hepatic Clearance for Organic Anion Transporting Polypeptide Substrate Drugs Between Different In Vitro-In Vivo Extrapolation Approaches.
J Pharm Sci
; 106(9): 2678-2687, 2017 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-28238896
17.
Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.
Genetics
; 170(1): 313-26, 2005 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-15744053
18.
E3024, 3-but-2-ynyl-5-methyl-2-piperazin-1-yl-3,5-dihydro-4H-imidazo[4,5-d]pyridazin-4-one tosylate, is a novel, selective and competitive dipeptidyl peptidase-IV inhibitor.
Eur J Pharmacol
; 548(1-3): 181-7, 2006 Oct 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-16973152
19.
How costly are ejaculates for Japanese macaques?
Primates
; 47(3): 272-4, 2006 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-16467956
20.
Comparison of androgen receptor CAG and GGN repeat length polymorphism in humans and apes.
Primates
; 47(3): 248-54, 2006 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-16467955