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1.
α-Melanocyte-stimulating hormone alleviates pathological cardiac remodeling via melanocortin 5 receptor.
EMBO Rep
; 25(4): 1987-2014, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-38454158
2.
Generation and characterisation of scalable and stable human pluripotent stem cell-derived microvascular-like endothelial cells for cardiac applications.
Angiogenesis
; 2024 May 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-38775849
3.
Conventional rigid 2D substrates cause complex contractile signals in monolayers of human induced pluripotent stem cell-derived cardiomyocytes.
J Physiol
; 600(3): 483-507, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34761809
4.
Protein Kinase A-Mediated Effects of Protein Kinase C Partial Agonist 5-(Hydroxymethyl)Isophthalate 1a3 in Colorectal Cancer Cells.
J Pharmacol Exp Ther
; 380(1): 54-62, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34697230
5.
Distinct Regulation of Cardiac Fibroblast Proliferation and Transdifferentiation by Classical and Novel Protein Kinase C Isoforms: Possible Implications for New Antifibrotic Therapies.
Mol Pharmacol
; 99(2): 104-113, 2021 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-33239332
6.
Rigorous Computational Study Reveals What Docking Overlooks: Double Trouble from Membrane Association in Protein Kinase C Modulators.
J Chem Inf Model
; 60(11): 5624-5633, 2020 11 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-32915560
7.
GATA4-targeted compound exhibits cardioprotective actions against doxorubicin-induced toxicity in vitro and in vivo: establishment of a chronic cardiotoxicity model using human iPSC-derived cardiomyocytes.
Arch Toxicol
; 94(6): 2113-2130, 2020 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32185414
8.
Stem cells are the most sensitive screening tool to identify toxicity of GATA4-targeted novel small-molecule compounds.
Arch Toxicol
; 92(9): 2897-2911, 2018 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-29987409
9.
Drug-Loaded Multifunctional Nanoparticles Targeted to the Endocardial Layer of the Injured Heart Modulate Hypertrophic Signaling.
Small
; 13(33)2017 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-28714245
10.
Cardiac fibrosis in myocardial infarction-from repair and remodeling to regeneration.
Cell Tissue Res
; 365(3): 563-81, 2016 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-27324127
11.
C1 domain-targeted isophthalates as protein kinase C modulators: structure-based design, structure-activity relationships and biological activities.
Biochem Soc Trans
; 42(6): 1543-9, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-25399568
12.
Affinity chromatography reveals direct binding of the GATA4-NKX2-5 interaction inhibitor (3i-1000) with GATA4.
Sci Rep
; 14(1): 8938, 2024 04 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-38637629
13.
Switching of hypertrophic signalling towards enhanced cardiomyocyte identity and maturity by a GATA4-targeted compound.
Stem Cell Res Ther
; 15(1): 5, 2024 01 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-38167208
14.
The C1 domain-targeted isophthalate derivative HMI-1b11 promotes neurite outgrowth and GAP-43 expression through PKCα activation in SH-SY5Y cells.
Pharmacol Res
; 73: 44-54, 2013 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-23643828
15.
Genome-wide profiling of miRNA-gene regulatory networks in mouse postnatal heart development-implications for cardiac regeneration.
Front Cardiovasc Med
; 10: 1148618, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37283582
16.
Expanding the Paradigm of Structure-Based Drug Design: Molecular Dynamics Simulations Support the Development of New Pyridine-Based Protein Kinase C-Targeted Agonists.
J Med Chem
; 66(7): 4588-4602, 2023 04 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-37010933
17.
Application of Human Induced Pluripotent Stem Cell Technology for Cardiovascular Regenerative Pharmacology.
Methods Mol Biol
; 2454: 163-196, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-33755910
18.
Pharmacological Protein Kinase C Modulators Reveal a Pro-hypertrophic Role for Novel Protein Kinase C Isoforms in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Front Pharmacol
; 11: 553852, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-33584253
19.
Cell adhesion and proliferation on common 3D printing materials used in stereolithography of microfluidic devices.
Lab Chip
; 20(13): 2372-2382, 2020 06 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-32500123
20.
Missing Selectivity of Targeted 4ß-Phorbol Prodrugs Expected to be Potential Chemotherapeutics.
ACS Med Chem Lett
; 11(5): 671-677, 2020 May 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-32435369