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1.
UBQLN2 and HSP70 participate in Parkin-mediated mitophagy by facilitating outer mitochondrial membrane rupture.
EMBO Rep
; 24(9): e55859, 2023 09 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-37501540
2.
Combined inhibition of pyruvate dehydrogenase kinase 1 and hexokinase 2 induces apoptsis in non-small cell lung cancer cell models.
Exp Cell Res
; 433(2): 113830, 2023 12 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37913974
3.
The interaction between E3 ubiquitin ligase Parkin and mitophagy receptor PHB2 links inner mitochondrial membrane ubiquitination to efficient mitophagy.
J Biol Chem
; 298(12): 102704, 2022 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-36379251
4.
Epigallocatechin gallate circumvents drug-induced resistance in non-small-cell lung cancer by modulating glucose metabolism and AMPK/AKT/MAPK axis.
Phytother Res
; 37(12): 5837-5853, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37621136
5.
Trichosanthin Promotes Anti-Tumor Immunity through Mediating Chemokines and Granzyme B Secretion in Hepatocellular Carcinoma.
Int J Mol Sci
; 24(2)2023 Jan 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-36674931
6.
A Model of Hereditary Sensory and Autonomic Neuropathy Type 1 Reveals a Role of Glycosphingolipids in Neuronal Polarity.
J Neurosci
; 39(29): 5816-5834, 2019 07 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-31138658
7.
Synthesis and biological effect of lysosome-targeting fluorescent anion transporters with enhanced anionophoric activity.
Bioorg Med Chem Lett
; 30(19): 127461, 2020 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32755679
8.
Identification of a Wells-Dawson polyoxometalate-based AP-2γ inhibitor with pro-apoptotic activity.
Biochem J
; 475(11): 1965-1977, 2018 06 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-29760237
9.
Liquid Chromatography-Tandem Mass Spectrometry Method Revealed that Lung Cancer Cells Exhibited Distinct Metabolite Profiles upon the Treatment with Different Pyruvate Dehydrogenase Kinase Inhibitors.
J Proteome Res
; 17(9): 3012-3021, 2018 09 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30028142
10.
Dichloroacetophenones targeting at pyruvate dehydrogenase kinase 1 with improved selectivity and antiproliferative activity: Synthesis and structure-activity relationships.
Bioorg Med Chem Lett
; 28(21): 3441-3445, 2018 11 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30266541
11.
Dual-target inhibitors of cholinesterase and GSK-3ß to modulate Alzheimer's disease.
Drug Discov Today
; 29(4): 103914, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-38340951
12.
Exploring casual effects and shared molecular mechanism between psoriasis and liver cancer through Mendelian randomization and comprehensive bioinformatic analyses.
Comput Biol Chem
; 110: 108089, 2024 Apr 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-38703750
13.
Evaluations of the neuroprotective effects of a dual-target isoquinoline inhibitor in the triple transgenic mouse model of Alzheimer's disease.
Neurosci Lett
; 802: 137166, 2023 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36889377
14.
Cytosolic malic enzyme and glucose-6-phosphate dehydrogenase modulate redox balance in NSCLC with acquired drug resistance.
FEBS J
; 290(19): 4792-4809, 2023 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-37410361
15.
Dichloroacetophenone biphenylsulfone ethers as anticancer pyruvate dehydrogenase kinase inhibitors in non-small cell lung cancer models.
Chem Biol Interact
; 378: 110467, 2023 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37004952
16.
Combined inhibition of pyruvate dehydrogenase kinase 1 and lactate dehydrogenase a induces metabolic and signaling reprogramming and enhances lung adenocarcinoma cell killing.
Cancer Lett
; 577: 216425, 2023 11 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-37805163
17.
Repurposing the Hedgehog pathway inhibitor, BMS-833923, as a phosphatidylglycerol-selective membrane-disruptive colistin adjuvant against ESKAPE pathogens.
Int J Antimicrob Agents
; 62(3): 106888, 2023 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-37328075
18.
Chlorpromazine affects autophagy in association with altered Rag GTPase-mTORC1-TFEB signaling.
Front Cell Dev Biol
; 11: 1266198, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37745295
19.
Pathological mechanisms and therapeutic strategies for Alzheimer's disease.
Neural Regen Res
; 17(3): 543-549, 2022 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-34380884
20.
Targeting glucose metabolism to develop anticancer treatments and therapeutic patents.
Expert Opin Ther Pat
; 32(4): 441-453, 2022 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-35001793