Detalles de la búsqueda
1.
Design and synthesis of novel pyrimido[4,5-b]azepine derivatives as HER2/EGFR dual inhibitors.
Bioorg Med Chem
; 21(8): 2250-2261, 2013 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23490150
2.
Design and synthesis of pyrrolo[3,2-d]pyrimidine HER2/EGFR dual inhibitors: improvement of the physicochemical and pharmacokinetic profiles for potent in vivo anti-tumor efficacy.
Bioorg Med Chem
; 20(20): 6171-80, 2012 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22980219
3.
Two Secreted Proteoglycans, Activators of Urothelial Cell-Cell Adhesion, Negatively Contribute to Bladder Cancer Initiation and Progression.
Cancers (Basel)
; 12(11)2020 Nov 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-33202923
4.
Anti-tumor efficacy of a novel CLK inhibitor via targeting RNA splicing and MYC-dependent vulnerability.
EMBO Mol Med
; 10(6)2018 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-29769258
5.
Panitumumab interaction with TAS-102 leads to combinational anticancer effects via blocking of EGFR-mediated tumor response to trifluridine.
Mol Oncol
; 11(8): 1065-1077, 2017 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-28486761
6.
Intratumor Heterogeneity in Primary Kidney Cancer Revealed by Metabolic Profiling of Multiple Spatially Separated Samples within Tumors.
EBioMedicine
; 19: 31-38, 2017 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-28408240
7.
Analyses of glutathione reductase hypomorphic mice indicate a genetic knockout.
Toxicol Sci
; 82(2): 367-73, 2004 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-15342956
8.
Stable transfection of Chinese hamster ovary cells with glutamate-cysteine ligase catalytic subunit cDNA confers increased resistance to tert-butyl hydroperoxide toxicity.
Toxicol Lett
; 136(2): 107-20, 2002 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-12425961
9.
HER2 and HER3 cooperatively regulate cancer cell growth and determine sensitivity to the novel investigational EGFR/HER2 kinase inhibitor TAK-285.
Oncoscience
; 1(3): 196-204, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-25594012
10.
Antitumor Activity of TAK-285, an Investigational, Non-Pgp Substrate HER2/EGFR Kinase Inhibitor, in Cultured Tumor Cells, Mouse and Rat Xenograft Tumors, and in an HER2-Positive Brain Metastasis Model.
J Cancer
; 4(7): 557-65, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-23983820
11.
Design and synthesis of pyrrolo[3,2-d]pyrimidine human epidermal growth factor receptor 2 (HER2)/epidermal growth factor receptor (EGFR) dual inhibitors: exploration of novel back-pocket binders.
J Med Chem
; 55(8): 3975-91, 2012 Apr 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-22439974
12.
Design and synthesis of novel human epidermal growth factor receptor 2 (HER2)/epidermal growth factor receptor (EGFR) dual inhibitors bearing a pyrrolo[3,2-d]pyrimidine scaffold.
J Med Chem
; 54(23): 8030-50, 2011 Dec 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-22003817
13.
Two newly identified genomic mutations in a Japanese female patient with fructose-1,6-bisphosphatase (FBPase) deficiency.
Mol Genet Metab
; 76(3): 207-10, 2002 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-12126934
Resultados
1 -
13
de 13
1
Próxima >
>>