Detalles de la búsqueda
1.
Predicting nonlinear relationships between external and internal concentrations with physiologically based pharmacokinetic modeling.
Toxicol Appl Pharmacol
; 440: 115922, 2022 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35176293
2.
Incorporating human exposure information in a weight of evidence approach to inform design of repeated dose animal studies.
Regul Toxicol Pharmacol
; 127: 105073, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-34743952
3.
Opportunities and challenges related to saturation of toxicokinetic processes: Implications for risk assessment.
Regul Toxicol Pharmacol
; 127: 105070, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-34718074
4.
A Systematic Review of Published Physiologically-based Kinetic Models and an Assessment of their Chemical Space Coverage.
Altern Lab Anim
; 49(5): 197-208, 2021 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-34836462
5.
PBPK model reporting template for chemical risk assessment applications.
Regul Toxicol Pharmacol
; 115: 104691, 2020 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-32502513
6.
A weight of evidence approach to investigate potential common mechanisms in pesticide groups to support cumulative risk assessment: A case study with dinitroaniline pesticides.
Regul Toxicol Pharmacol
; 107: 104419, 2019 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-31301330
7.
Developing a Physiologically-Based Pharmacokinetic Model Knowledgebase in Support of Provisional Model Construction.
PLoS Comput Biol
; 12(2): e1004495, 2016 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-26871706
8.
Investigating the state of physiologically based kinetic modelling practices and challenges associated with gaining regulatory acceptance of model applications.
Regul Toxicol Pharmacol
; 90: 104-115, 2017 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-28866268
9.
Adverse Outcome Pathways-Organizing Toxicological Information to Improve Decision Making.
J Pharmacol Exp Ther
; 356(1): 170-81, 2016 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-26537250
10.
Evaluating the Impact of Uncertainties in Clearance and Exposure When Prioritizing Chemicals Screened in High-Throughput Assays.
Environ Sci Technol
; 50(11): 5961-71, 2016 06 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-27124219
11.
Conceptual Framework To Extend Life Cycle Assessment Using Near-Field Human Exposure Modeling and High-Throughput Tools for Chemicals.
Environ Sci Technol
; 50(21): 11922-11934, 2016 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27668689
12.
Completing the Link between Exposure Science and Toxicology for Improved Environmental Health Decision Making: The Aggregate Exposure Pathway Framework.
Environ Sci Technol
; 50(9): 4579-86, 2016 05 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-26759916
13.
Reconstructing exposures from biomarkers using exposure-pharmacokinetic modeling--A case study with carbaryl.
Regul Toxicol Pharmacol
; 73(3): 689-98, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26545325
14.
Improving the risk assessment of lipophilic persistent environmental chemicals in breast milk.
Crit Rev Toxicol
; 44(7): 600-17, 2014 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-25068490
15.
A new method for generating distributions of biomonitoring equivalents to support exposure assessment and prioritization.
Regul Toxicol Pharmacol
; 69(3): 434-42, 2014 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-24845241
16.
Bi-allelic variants in DNAH3 cause male infertility with asthenoteratozoospermia in humans and mice.
Hum Reprod Open
; 2024(1): hoae003, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-38312775
17.
Trust your gut: Establishing confidence in gastrointestinal models - An overview of the state of the science and contexts of use.
ALTEX
; 2024 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-38898799
18.
Challenges and opportunities for overcoming dog use in agrochemical evaluation and registration.
ALTEX
; 40(3): 534-540, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-36888967
19.
Reconstructing human exposures using biomarkers and other "clues".
J Toxicol Environ Health B Crit Rev
; 15(1): 22-38, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22202228
20.
IVIVE: Facilitating the Use of In Vitro Toxicity Data in Risk Assessment and Decision Making.
Toxics
; 10(5)2022 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35622645