Detalles de la búsqueda
1.
M1/M4 receptors as potential therapeutic treatments for schizophrenia: A comprehensive study.
Bioorg Med Chem
; 105: 117728, 2024 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-38640587
2.
Review and prospects of targeted therapies for Spleen tyrosine kinase (SYK).
Bioorg Med Chem
; 96: 117514, 2023 12 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37984216
3.
Uptake, Translocation, and Fate of Carcinogenic Aristolochic Acid in Typical Vegetables in Soil-Plant Systems.
Molecules
; 27(23)2022 Nov 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-36500364
4.
An Integrated Tumor Microenvironment Responsive Polymeric Micelle for Smart Drug Delivery and Effective Drug Release.
Bioconjug Chem
; 32(9): 2083-2094, 2021 09 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-34472841
5.
The discovery of quinoline derivatives, as NF-κB inducing kinase (NIK) inhibitors with anti-inflammatory effects in vitro, low toxicities against T cell growth.
Bioorg Med Chem
; 29: 115856, 2021 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33199201
6.
ß-Functionalization of Indolin-2-one-Derived Aliphatic Acids for the Divergent Synthesis of Spirooxindole γ-Butyrolactones.
J Org Chem
; 82(8): 4186-4193, 2017 04 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-28326774
7.
Rational design, synthesis, and biological evaluation of Pan-Raf inhibitors to overcome resistance.
Org Biomol Chem
; 15(16): 3455-3465, 2017 Apr 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-28368067
8.
Potent Pan-Raf and Receptor Tyrosine Kinase Inhibitors Based on a Cyclopropyl Formamide Fragment Overcome Resistance.
J Chem Inf Model
; 57(6): 1439-1452, 2017 06 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-28485964
9.
Access to Spiro and Fused Indole Derivatives from α,ß-Unsaturated Aldehydes Enabled by N-Heterocyclic Carbene Catalysis.
Chem Rec
; 16(3): 1489-500, 2016 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-27185290
10.
Targeting epigenetic reader and eraser: Rational design, synthesis and in vitro evaluation of dimethylisoxazoles derivatives as BRD4/HDAC dual inhibitors.
Bioorg Med Chem Lett
; 26(12): 2931-2935, 2016 06 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27142751
11.
Expression of TGF-ß1 and CTGF Is Associated with Fibrosis of Denervated Sternocleidomastoid Muscles in Mice.
Tohoku J Exp Med
; 238(1): 49-56, 2016 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26686381
12.
Synthesis and Biological Evaluation of 1-(2-Aminophenyl)-3-arylurea Derivatives as Potential EphA2 and HDAC Dual Inhibitors.
Chem Pharm Bull (Tokyo)
; 64(8): 1136-41, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27477652
13.
N-Heterocyclic Carbene-Catalyzed Formal [3 + 2] Annulation of α-Bromoenals with 3-Aminooxindoles: A Stereoselective Synthesis of Spirooxindole γ-Butyrolactams.
J Org Chem
; 80(22): 11593-7, 2015 Nov 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-26506021
14.
N-Heterocyclic carbene-catalyzed annulation of cyclic ß-enamino esters with enals: access to functionalized indolo[2,3-a]quinolizidines.
Org Biomol Chem
; 13(16): 4661-7, 2015 Apr 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-25799005
15.
Cooperative N-heterocyclic carbene (NHC)-Lewis acid-mediated regioselective umpolung formal [3 + 2] annulations of alkynyl aldehydes with isatins.
Org Biomol Chem
; 12(19): 3009-15, 2014 May 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-24718717
16.
Design, Synthesis, and Biological Evaluation of a Novel NIK Inhibitor with Anti-Inflammatory and Hepatoprotective Effects for Sepsis Treatment.
J Med Chem
; 67(7): 5617-5641, 2024 Apr 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-38563549
17.
Efficacy and safety of anlotinib-based chemotherapy for locally advanced or metastatic anaplastic thyroid carcinoma.
Endocrine
; 81(3): 540-546, 2023 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37219702
18.
Discovery of 3-(1H-benzo[d]imidazole-2-yl)-1H-pyrazol-4 -amine derivatives as novel and potent syk inhibitors for the treatment of hematological malignancies.
Eur J Med Chem
; 258: 115597, 2023 Oct 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37423126
19.
Design, synthesis and biological evaluation of ß-carboline derivatives as novel inhibitors targeting B-Raf kinase.
Bioorg Med Chem Lett
; 22(14): 4783-6, 2012 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22704238
20.
Racial Disparities in Survival of Breast Cancer Patients After Surgery.
Front Public Health
; 10: 831906, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35646795