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1.
Leukaemia hijacks a neural mechanism to invade the central nervous system.
Nature
; 560(7716): 55-60, 2018 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-30022166
2.
IGF1R as druggable target mediating PI3K-δ inhibitor resistance in a murine model of chronic lymphocytic leukemia.
Blood
; 134(6): 534-547, 2019 08 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31010847
3.
Combinatorial efficacy of entospletinib and chemotherapy in patient-derived xenograft models of infant acute lymphoblastic leukemia.
Haematologica
; 106(4): 1067-1078, 2021 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32414848
4.
Dissection of the Effects of JAK and BTK Inhibitors on the Functionality of Healthy and Malignant Lymphocytes.
J Immunol
; 203(8): 2100-2109, 2019 10 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31511358
5.
The PI3Kδ-Selective Inhibitor Idelalisib Minimally Interferes with Immune Effector Function Mediated by Rituximab or Obinutuzumab and Significantly Augments B Cell Depletion In Vivo.
J Immunol
; 200(7): 2304-2312, 2018 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29453281
6.
Targeting PI3Kδ function for amelioration of murine chronic graft-versus-host disease.
Am J Transplant
; 19(6): 1820-1830, 2019 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-30748099
7.
GS-5759, a Bifunctional ß2-Adrenoceptor Agonist and Phosphodiesterase 4 Inhibitor for Chronic Obstructive Pulmonary Disease with a Unique Mode of Action: Effects on Gene Expression in Human Airway Epithelial Cells.
J Pharmacol Exp Ther
; 360(2): 324-340, 2017 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-27927912
8.
The in vitro pharmacology of GS-5759, a novel bifunctional phosphodiesterase 4 inhibitor and long acting ß2-adrenoceptor agonist.
J Pharmacol Exp Ther
; 349(1): 85-93, 2014 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-24513870
9.
Combination of roflumilast with a beta-2 adrenergic receptor agonist inhibits proinflammatory and profibrotic mediator release from human lung fibroblasts.
Respir Res
; 13: 28, 2012 Mar 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-22452977
10.
Additive anti-inflammatory effects of beta 2 adrenoceptor agonists or glucocorticosteroid with roflumilast in human peripheral blood mononuclear cells.
Pulm Pharmacol Ther
; 25(2): 178-84, 2012 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-22306235
11.
The receptor of the colony-stimulating factor-1 (CSF-1R) is a novel prognostic factor and therapeutic target in follicular lymphoma.
Leukemia
; 35(9): 2635-2649, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-33731849
12.
PI3Kδ inhibition reshapes follicular lymphoma-immune microenvironment cross talk and unleashes the activity of venetoclax.
Blood Adv
; 4(17): 4217-4231, 2020 09 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-32898249
13.
A novel ex vivo high-throughput assay reveals antiproliferative effects of idelalisib and ibrutinib in chronic lymphocytic leukemia.
Oncotarget
; 9(40): 26019-26031, 2018 May 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-29899839
14.
PI3Kδ inhibitor idelalisib in combination with BTK inhibitor ONO/GS-4059 in diffuse large B cell lymphoma with acquired resistance to PI3Kδ and BTK inhibitors.
PLoS One
; 12(2): e0171221, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28178345
15.
Integrated genomic characterization of IDH1-mutant glioma malignant progression.
Nat Genet
; 48(1): 59-66, 2016 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-26618343
16.
Transforming potential of alternatively spliced variants of fibroblast growth factor receptor 2 in human mammary epithelial cells.
Mol Cancer Res
; 2(11): 643-52, 2004 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-15561780
17.
The in vivo efficacy and side effect pharmacology of GS-5759, a novel bifunctional phosphodiesterase 4 inhibitor and long-acting ß 2-adrenoceptor agonist in preclinical animal species.
Pharmacol Res Perspect
; 2(4): e00046, 2014 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-25505595
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