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1.
GS-5759, a Bifunctional ß2-Adrenoceptor Agonist and Phosphodiesterase 4 Inhibitor for Chronic Obstructive Pulmonary Disease with a Unique Mode of Action: Effects on Gene Expression in Human Airway Epithelial Cells.
J Pharmacol Exp Ther
; 360(2): 324-340, 2017 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-27927912
2.
The in vitro pharmacology of GS-5759, a novel bifunctional phosphodiesterase 4 inhibitor and long acting ß2-adrenoceptor agonist.
J Pharmacol Exp Ther
; 349(1): 85-93, 2014 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-24513870
3.
Combination of roflumilast with a beta-2 adrenergic receptor agonist inhibits proinflammatory and profibrotic mediator release from human lung fibroblasts.
Respir Res
; 13: 28, 2012 Mar 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-22452977
4.
Additive anti-inflammatory effects of beta 2 adrenoceptor agonists or glucocorticosteroid with roflumilast in human peripheral blood mononuclear cells.
Pulm Pharmacol Ther
; 25(2): 178-84, 2012 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-22306235
5.
PI3Kδ inhibitor idelalisib in combination with BTK inhibitor ONO/GS-4059 in diffuse large B cell lymphoma with acquired resistance to PI3Kδ and BTK inhibitors.
PLoS One
; 12(2): e0171221, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28178345
6.
Integrated genomic characterization of IDH1-mutant glioma malignant progression.
Nat Genet
; 48(1): 59-66, 2016 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-26618343
7.
Transforming potential of alternatively spliced variants of fibroblast growth factor receptor 2 in human mammary epithelial cells.
Mol Cancer Res
; 2(11): 643-52, 2004 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-15561780
8.
The in vivo efficacy and side effect pharmacology of GS-5759, a novel bifunctional phosphodiesterase 4 inhibitor and long-acting ß 2-adrenoceptor agonist in preclinical animal species.
Pharmacol Res Perspect
; 2(4): e00046, 2014 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-25505595
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