Búsqueda | Biblioteca Virtual en Salud

1.

Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.

Herold, C; Hooli, B V; Mullin, K; Liu, T; Roehr, J T; Mattheisen, M; Parrado, A R; Bertram, L; Lange, C; Tanzi, R E.

Mol Psychiatry ; 21(11): 1608-1612, 2016 11.

Artículo en Inglés | MEDLINE | ID: mdl-26830138

2.

Rare autosomal copy number variations in early-onset familial Alzheimer's disease.

Hooli, B V; Kovacs-Vajna, Z M; Mullin, K; Blumenthal, M A; Mattheisen, M; Zhang, C; Lange, C; Mohapatra, G; Bertram, L; Tanzi, R E.

Mol Psychiatry ; 19(6): 676-81, 2014 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-23752245

3.

Isolation and characterization of APLP2 encoding a homologue of the Alzheimer's associated amyloid beta protein precursor.

Wasco, W; Gurubhagavatula, S; Paradis, M D; Romano, D M; Sisodia, S S; Hyman, B T; Neve, R L; Tanzi, R E.

Nat Genet ; 5(1): 95-100, 1993 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-8220435

4.

Mapping, cloning and genetic characterization of the region containing the Wilson disease gene.

Petrukhin, K; Fischer, S G; Pirastu, M; Tanzi, R E; Chernov, I; Devoto, M; Brzustowicz, L M; Cayanis, E; Vitale, E; Russo, J J.

Nat Genet ; 5(4): 338-43, 1993 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-8298640

5.

The Wilson disease gene is a copper transporting ATPase with homology to the Menkes disease gene.

Tanzi, R E; Petrukhin, K; Chernov, I; Pellequer, J L; Wasco, W; Ross, B; Romano, D M; Parano, E; Pavone, L; Brzustowicz, L M.

Nat Genet ; 5(4): 344-50, 1993 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-8298641

6.

Alpha-2 macroglobulin is genetically associated with Alzheimer disease.

Blacker, D; Wilcox, M A; Laird, N M; Rodes, L; Horvath, S M; Go, R C; Perry, R; Watson, B; Bassett, S S; McInnis, M G; Albert, M S; Hyman, B T; Tanzi, R E.

Nat Genet ; 19(4): 357-60, 1998 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-9697696

7.

Genetic evidence for a novel familial Alzheimer's disease locus on chromosome 14.

St George-Hyslop, P; Haines, J; Rogaev, E; Mortilla, M; Vaula, G; Pericak-Vance, M; Foncin, J F; Montesi, M; Bruni, A; Sorbi, S; Rainero, I; Pinessi, L; Pollen, D; Polinsky, R; Nee, L; Kennedy, J; Macciardi, F; Rogaeva, E; Liang, Y; Alexandrova, N; Lukiw, W; Schlumpf, K; Tanzi, R; Tsuda, T; Farrer, L; Cantu, J M; Duara, R; Amaducci, L; Bergamini, L; Gusella, J; Roses, A; Crapper McLachlan, D.

Nat Genet ; 2(4): 330-4, 1992 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-1303289

8.

Acyl-coenzyme A: cholesterol acyltransferase modulates the generation of the amyloid beta-peptide.

Puglielli, L; Konopka, G; Pack-Chung, E; Ingano, L A; Berezovska, O; Hyman, B T; Chang, T Y; Tanzi, R E; Kovacs, D M.

Nat Cell Biol ; 3(10): 905-12, 2001 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-11584272

9.

Uptake of HIV-1 tat protein mediated by low-density lipoprotein receptor-related protein disrupts the neuronal metabolic balance of the receptor ligands.

Liu, Y; Jones, M; Hingtgen, C M; Bu, G; Laribee, N; Tanzi, R E; Moir, R D; Nath, A; He, J J.

Nat Med ; 6(12): 1380-7, 2000 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-11100124

10.

Alzheimer-associated presenilins 1 and 2: neuronal expression in brain and localization to intracellular membranes in mammalian cells.

Kovacs, D M; Fausett, H J; Page, K J; Kim, T W; Moir, R D; Merriam, D E; Hollister, R D; Hallmark, O G; Mancini, R; Felsenstein, K M; Hyman, B T; Tanzi, R E; Wasco, W.

Nat Med ; 2(2): 224-9, 1996 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-8574969

11.

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease.

Nat Med ; 2(8): 864-70, 1996 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-8705854

12.

Non-Amyloid Approaches to Disease Modification for Alzheimer's Disease: An EU/US CTAD Task Force Report.

Gauthier, Serge; Aisen, P S; Cummings, J; Detke, M J; Longo, F M; Raman, R; Sabbagh, M; Schneider, L; Tanzi, R; Tariot, P; Weiner, M; Touchon, J; Vellas, B.

J Prev Alzheimers Dis ; 7(3): 152-157, 2020.

Artículo en Inglés | MEDLINE | ID: mdl-32420298

13.

Negative regulation of the SAPK/JNK signaling pathway by presenilin 1.

Kim, J W; Chang, T S; Lee, J E; Huh, S H; Yeon, S W; Yang, W S; Joe, C O; Mook-Jung, I; Tanzi, R E; Kim, T W; Choi, E J.

J Cell Biol ; 153(3): 457-63, 2001 Apr 30.

Artículo en Inglés | MEDLINE | ID: mdl-11331298

14.

Genetics of aging.

Finch, C E; Tanzi, R E.

Science ; 278(5337): 407-11, 1997 Oct 17.

Artículo en Inglés | MEDLINE | ID: mdl-9334291

15.

The amyloid beta protein gene is not duplicated in brains from patients with Alzheimer's disease.

Tanzi, R E; Bird, E D; Latt, S A; Neve, R L.

Science ; 238(4827): 666-9, 1987 Oct 30.

Artículo en Inglés | MEDLINE | ID: mdl-2890207

16.

Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a caspase-3 family protease.

Kim, T W; Pettingell, W H; Jung, Y K; Kovacs, D M; Tanzi, R E.

Science ; 277(5324): 373-6, 1997 Jul 18.

Artículo en Inglés | MEDLINE | ID: mdl-9219695

17.

Evidence for genetic linkage of Alzheimer's disease to chromosome 10q.

Bertram, L; Blacker, D; Mullin, K; Keeney, D; Jones, J; Basu, S; Yhu, S; McInnis, M G; Go, R C; Vekrellis, K; Selkoe, D J; Saunders, A J; Tanzi, R E.

Science ; 290(5500): 2302-3, 2000 Dec 22.

Artículo en Inglés | MEDLINE | ID: mdl-11125142

18.

Rapid induction of Alzheimer A beta amyloid formation by zinc.

Bush, A I; Pettingell, W H; Multhaup, G; d Paradis, M; Vonsattel, J P; Gusella, J F; Beyreuther, K; Masters, C L; Tanzi, R E.

Science ; 265(5177): 1464-7, 1994 Sep 02.

Artículo en Inglés | MEDLINE | ID: mdl-8073293

19.

Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus.

Tanzi, R E; Gusella, J F; Watkins, P C; Bruns, G A; St George-Hyslop, P; Van Keuren, M L; Patterson, D; Pagan, S; Kurnit, D M; Neve, R L.

Science ; 235(4791): 880-4, 1987 Feb 20.

Artículo en Inglés | MEDLINE | ID: mdl-2949367

20.

Absence of duplication of chromosome 21 genes in familial and sporadic Alzheimer's disease.

St George-Hyslop, P H; Tanzi, R E; Polinsky, R J; Neve, R L; Pollen, D; Drachman, D; Growdon, J; Cupples, L A; Nee, L; Myers, R H.

Science ; 238(4827): 664-6, 1987 Oct 30.

Artículo en Inglés | MEDLINE | ID: mdl-2890206

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