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1.
TBK1 directly engages Akt/PKB survival signaling to support oncogenic transformation.
Mol Cell
; 41(4): 458-70, 2011 Feb 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-21329883
2.
Discovery of imidazopyridazines as potent Pim-1/2 kinase inhibitors.
Bioorg Med Chem Lett
; 26(22): 5580-5590, 2016 11 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27769621
3.
Discovery of 5-(1H-indol-5-yl)-1,3,4-thiadiazol-2-amines as potent PIM inhibitors.
Bioorg Med Chem Lett
; 25(4): 775-80, 2015 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25616902
4.
The discovery of novel 3-(pyrazin-2-yl)-1H-indazoles as potent pan-Pim kinase inhibitors.
Bioorg Med Chem Lett
; 25(4): 834-40, 2015 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25597005
5.
The discovery and optimization of aminooxadiazoles as potent Pim kinase inhibitors.
Bioorg Med Chem Lett
; 25(4): 847-55, 2015 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25599837
6.
Rib fracture as a complication of erroneous baseplate and inferior screw placement in reverse total shoulder replacement: a case report.
J Shoulder Elbow Surg
; 29(3): e87-e92, 2020 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-32067713
7.
Phosphoinositide-3-kinase inhibitors: evaluation of substituted alcohols as replacements for the piperazine sulfonamide portion of AMG 511.
Bioorg Med Chem Lett
; 24(24): 5630-5634, 2014 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25466188
8.
Identification of triazolopyridazinones as potent p38α inhibitors.
Bioorg Med Chem Lett
; 22(2): 1226-9, 2012 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22196117
9.
Isoform-selective thiazolo[5,4-b]pyridine S1P1 agonists possessing acyclic amino carboxylate head-groups.
Bioorg Med Chem Lett
; 22(4): 1779-83, 2012 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22257889
10.
Quinolinone-based agonists of S1P1: use of a N-scan SAR strategy to optimize in vitro and in vivo activity.
Bioorg Med Chem Lett
; 22(1): 527-31, 2012 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22104144
11.
Implementing the "Getting It Right First Time" (GIRFT) Report Recommendations: The Results of Introducing a Shoulder and Elbow Multidisciplinary Team.
Cureus
; 14(3): e23338, 2022 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-35464564
12.
Dual Surgeon Operating in Reverse Geometry Total Shoulder Replacement: The Learning Curve and Its Effects on Complication Rates.
Cureus
; 14(3): e23337, 2022 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-35464579
13.
Part 2: Structure-activity relationship (SAR) investigations of fused pyrazoles as potent, selective and orally available inhibitors of p38alpha mitogen-activated protein kinase.
Bioorg Med Chem Lett
; 20(5): 1680-4, 2010 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20138761
14.
2-Aminothiadiazole inhibitors of AKT1 as potential cancer therapeutics.
Bioorg Med Chem Lett
; 20(5): 1652-6, 2010 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20137932
15.
The discovery of an orally efficacious positive allosteric modulator of the calcium sensing receptor containing a dibenzylamine core.
Bioorg Med Chem Lett
; 20(18): 5544-7, 2010 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20708930
16.
Broad antitumor activity in breast cancer xenografts by motesanib, a highly selective, oral inhibitor of vascular endothelial growth factor, platelet-derived growth factor, and Kit receptors.
Clin Cancer Res
; 15(1): 110-8, 2009 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19118038
17.
Part 1: Structure-Activity Relationship (SAR) investigations of fused pyrazoles as potent, selective and orally available inhibitors of p38alpha mitogen-activated protein kinase.
Bioorg Med Chem Lett
; 19(16): 4724-8, 2009 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19574047
18.
Discovery of ( R)-8-(6-Methyl-4-oxo-1,4,5,6-tetrahydropyrrolo[3,4- b]pyrrol-2-yl)-3-(1-methylcyclopropyl)-2-((1-methylcyclopropyl)amino)quinazolin-4(3 H)-one, a Potent and Selective Pim-1/2 Kinase Inhibitor for Hematological Malignancies.
J Med Chem
; 62(3): 1523-1540, 2019 02 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-30624936
19.
Discovery of aryl aminoquinazoline pyridones as potent, selective, and orally efficacious inhibitors of receptor tyrosine kinase c-Kit.
J Med Chem
; 51(11): 3065-8, 2008 Jun 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-18447379
20.
Evaluation of a series of naphthamides as potent, orally active vascular endothelial growth factor receptor-2 tyrosine kinase inhibitors.
J Med Chem
; 51(6): 1668-80, 2008 Mar 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-18324759