Detalles de la búsqueda
1.
Phase 1 drug-drug interaction study to assess the effect of CYP3A4 inhibition and pan-CYP induction on the pharmacokinetics and safety of fosmanogepix in healthy participants.
Antimicrob Agents Chemother
; : e0165023, 2024 May 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-38757982
2.
Pharmacokinetics, safety, and tolerability of fosmanogepix IV to oral switch and multiple IV doses in healthy participants.
Antimicrob Agents Chemother
; 68(5): e0145523, 2024 May 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-38551346
3.
Safety and Pharmacokinetics of Intravenous and Oral Fosmanogepix, a First-in-Class Antifungal Agent, in Healthy Volunteers.
Antimicrob Agents Chemother
; 67(4): e0162322, 2023 04 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-36988461
4.
Clinical Efficacy and Safety of a Novel Antifungal, Fosmanogepix, in Patients with Candidemia Caused by Candida auris: Results from a Phase 2 Trial.
Antimicrob Agents Chemother
; 67(5): e0141922, 2023 05 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-37022196
5.
Phase 1b safety and pharmacokinetics of intravenous and oral fosmanogepix in patients with acute myeloid leukaemia and neutropenia.
J Antimicrob Chemother
; 78(11): 2645-2652, 2023 11 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-37681450
6.
Efficacy and safety of ceftazidime/avibactam in patients with infections caused by ß-lactamase-producing Gram-negative pathogens: a pooled analysis from the Phase 3 clinical trial programme.
J Antimicrob Chemother
; 78(11): 2672-2682, 2023 11 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-37700689
7.
Clinical safety and efficacy of novel antifungal, fosmanogepix, for the treatment of candidaemia: results from a Phase 2 trial.
J Antimicrob Chemother
; 78(10): 2471-2480, 2023 10 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-37596890
8.
In Vitro Activity of Ceftazidime-Avibactam against Isolates from Respiratory and Blood Specimens from Patients with Nosocomial Pneumonia, Including Ventilator-Associated Pneumonia, in a Phase 3 Clinical Trial.
Antimicrob Agents Chemother
; 64(5)2020 04 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-32071051
9.
Considerations in the Selection of Renal Dosage Adjustments for Patients with Serious Infections and Lessons Learned from the Development of Ceftazidime-Avibactam.
Antimicrob Agents Chemother
; 64(4)2020 03 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-32015049
10.
Evaluation of anidulafungin in the treatment of intra-abdominal candidiasis: a pooled analysis of patient-level data from 5 prospective studies.
Eur J Clin Microbiol Infect Dis
; 38(10): 1849-1856, 2019 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-31280481
11.
Retrospective cohort study comparing the risk of severe hepatotoxicity in hospitalized patients treated with echinocandins for invasive candidiasis in the presence of confounding by indication.
BMC Infect Dis
; 18(1): 438, 2018 Aug 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-30157797
12.
Tofacitinib versus etanercept or placebo in moderate-to-severe chronic plaque psoriasis: a phase 3 randomised non-inferiority trial.
Lancet
; 386(9993): 552-61, 2015 Aug 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-26051365
13.
HIV economic burden of illness in the Veterans Health Administration population.
AIDS Care
; 27(1): 123-31, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25225150
14.
Efficacy and safety of lersivirine versus etravirine for the treatment of HIV-1 infection in patients with prior non-nucleoside reverse transcriptase inhibitor (NNRTI) use and evidence of NNRTI resistance: a randomized phase 2B trial.
HIV Clin Trials
; 15(5): 209-17, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-25350959
15.
Review of the impact of NNRTI-based HIV treatment regimens on patient-reported disease burden.
AIDS Care
; 26(4): 466-75, 2014 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-24111805
16.
Ceftazidime-Avibactam in the Treatment of Patients with Bacteremia or Nosocomial Pneumonia: A Systematic Review and Meta-analysis.
Infect Dis Ther
; 2024 May 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-38822167
17.
Responsiveness of the MOS-HIV and EQ-5D in HIV-infected adults receiving antiretroviral therapies.
Health Qual Life Outcomes
; 11: 42, 2013 Mar 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-23497257
18.
Patient reported outcome instruments used in clinical trials of HIV-infected adults on NNRTI-based therapy: a 10-year review.
Health Qual Life Outcomes
; 11: 164, 2013 Oct 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-24090055
19.
No effect of a single supratherapeutic dose of lersivirine, a next-generation nonnucleoside reverse transcriptase inhibitor, on corrected QT interval in healthy subjects.
Antimicrob Agents Chemother
; 56(5): 2408-13, 2012 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-22371898
20.
Effect of rifampin and rifabutin on the pharmacokinetics of lersivirine and effect of lersivirine on the pharmacokinetics of rifabutin and 25-O-desacetyl-rifabutin in healthy subjects.
Antimicrob Agents Chemother
; 56(8): 4303-9, 2012 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-22644026