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1.
Relevance of primary lesion location, tumour heterogeneity and genetic mutation demonstrated through tumour growth inhibition and overall survival modelling in metastatic colorectal cancer.
Br J Clin Pharmacol
; 88(1): 166-177, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34087010
2.
Population pharmacokinetic model selection assisted by machine learning.
J Pharmacokinet Pharmacodyn
; 49(2): 257-270, 2022 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-34708337
3.
Fast screening of covariates in population models empowered by machine learning.
J Pharmacokinet Pharmacodyn
; 48(4): 597-609, 2021 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-34019213
4.
Machine Learning in Modeling Disease Trajectory and Treatment Outcomes: An Emerging Enabler for Model-Informed Precision Medicine.
Clin Pharmacol Ther
; 115(4): 720-726, 2024 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-38105646
5.
Tumor growth inhibition modeling in patients with second line biliary tract cancer and first line non-small cell lung cancer based on bintrafusp alfa trials.
CPT Pharmacometrics Syst Pharmacol
; 13(1): 143-153, 2024 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-38087967
6.
Artificial Intelligence for Quantitative Modeling in Drug Discovery and Development: An Innovation and Quality Consortium Perspective on Use Cases and Best Practices.
Clin Pharmacol Ther
; 115(4): 658-672, 2024 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-37716910
7.
Current Status and Future Directions: The Application of Artificial Intelligence/Machine Learning for Precision Medicine.
Clin Pharmacol Ther
; 115(4): 673-686, 2024 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-38103204
8.
Semiautomated Pipeline to Quantify Tumor Evolution From Real-World Positron Emission Tomography/Computed Tomography Imaging.
JCO Clin Cancer Inform
; 7: e2200126, 2023 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37146261
9.
Modeling tumor size dynamics based on real-world electronic health records and image data in advanced melanoma patients receiving immunotherapy.
CPT Pharmacometrics Syst Pharmacol
; 12(8): 1170-1181, 2023 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37328961
10.
Mouse embryonic stem cells that survive γ-rays exposure maintain pluripotent differentiation potential and genome stability.
J Cell Physiol
; 227(3): 1242-9, 2012 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-21732352
11.
Model-informed assessment of ethnic sensitivity and dosage justification for Asian populations in the global clinical development and use of cladribine tablets.
Clin Transl Sci
; 15(2): 297-308, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34704362
12.
Predicting disease activity in patients with multiple sclerosis: An explainable machine-learning approach in the Mavenclad trials.
CPT Pharmacometrics Syst Pharmacol
; 11(7): 843-853, 2022 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-35521742
13.
Pharmacometric modeling and machine learning analyses of prognostic and predictive factors in the JAVELIN Gastric 100 phase III trial of avelumab.
CPT Pharmacometrics Syst Pharmacol
; 11(3): 333-347, 2022 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-34971492
14.
Application of Machine Learning in Translational Medicine: Current Status and Future Opportunities.
AAPS J
; 23(4): 74, 2021 05 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-34008139
15.
Population pharmacokinetics of ATR inhibitor berzosertib in phase I studies for different cancer types.
Cancer Chemother Pharmacol
; 87(2): 185-196, 2021 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-33145616
16.
Machine Learning Analysis of Individual Tumor Lesions in Four Metastatic Colorectal Cancer Clinical Studies: Linking Tumor Heterogeneity to Overall Survival.
AAPS J
; 22(3): 58, 2020 03 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-32185612
17.
Effects of Postponing Treatment in the Second Year of Cladribine Administration: Clinical Trial Simulation Analysis of Absolute Lymphocyte Counts and Relapse Rate in Patients with Relapsing-Remitting Multiple Sclerosis.
Clin Pharmacokinet
; 58(3): 325-333, 2019 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-29992396
18.
The Clinical Pharmacology of Cladribine Tablets for the Treatment of Relapsing Multiple Sclerosis.
Clin Pharmacokinet
; 58(3): 283-297, 2019 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-29987837
19.
Correction to: The Clinical Pharmacology of Cladribine Tablets for the Treatment of Relapsing Multiple Sclerosis.
Clin Pharmacokinet
; 58(3): 401, 2019 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-30066294
20.
Assessing Similarity Among Individual Tumor Size Lesion Dynamics: The CICIL Methodology.
CPT Pharmacometrics Syst Pharmacol
; 7(4): 228-236, 2018 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29388396