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1.
Topoisomerase 1 inhibits MYC promoter activity by inducing G-quadruplex formation.
Nucleic Acids Res
; 50(11): 6332-6342, 2022 06 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-35687110
2.
Rolling Circle Enhanced Detection of Specific Restriction Endonuclease Activities in Crude Cell Extracts.
Sensors (Basel)
; 22(20)2022 Oct 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-36298113
3.
The human DNA topoisomerase I mutant Gly717Asp: Higher religation rate is not always associated with camptothecin resistance.
Arch Biochem Biophys
; 663: 165-172, 2019 03 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30653963
4.
Topoisomerase I activity and sensitivity to camptothecin in breast cancer-derived cells: a comparative study.
BMC Cancer
; 19(1): 1158, 2019 Nov 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-31783818
5.
Real-time analysis of cleavage and religation activity of human topoisomerase 1 based on ternary fluorescence resonance energy transfer DNA substrate.
Arch Biochem Biophys
; 643: 1-6, 2018 04 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-29458004
6.
Mutation of Gly717Phe in human topoisomerase 1B has an effect on enzymatic function, reactivity to the camptothecin anticancer drug and on the linker domain orientation.
Biochim Biophys Acta
; 1854(8): 860-8, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-25910424
7.
The human topoisomerase 1B Arg634Ala mutation results in camptothecin resistance and loss of inter-domain motion correlation.
Biochim Biophys Acta
; 1834(12): 2712-21, 2013 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-24096022
8.
Rolling circle amplification-based detection of human topoisomerase I activity on magnetic beads.
Anal Biochem
; 451: 42-4, 2014 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24525043
9.
Molecular mechanism of the camptothecin resistance of Glu710Gly topoisomerase IB mutant analyzed in vitro and in silico.
Mol Cancer
; 12(1): 100, 2013 Sep 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-24004603
10.
Phosphorylation of the Human DNA Glycosylase NEIL2 Is Affected by Oxidative Stress and Modulates Its Activity.
Antioxidants (Basel)
; 12(2)2023 Feb 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-36829914
11.
Gel-Free Tools for Quick and Simple Screening of Anti-Topoisomerase 1 Compounds.
Pharmaceuticals (Basel)
; 16(5)2023 Apr 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-37242440
12.
Interaction between natural compounds and human topoisomerase I.
Biol Chem
; 393(11): 1327-40, 2012 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-23109546
13.
Simple and Fast Rolling Circle Amplification-Based Detection of Topoisomerase 1 Activity in Crude Biological Samples.
J Vis Exp
; (190)2022 12 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-36533843
14.
Genetic and Molecular Characterization of the Immortalized Murine Hepatic Stellate Cell Line GRX.
Cells
; 11(9)2022 04 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-35563813
15.
Erybraedin C, a natural compound from the plant Bituminaria bituminosa, inhibits both the cleavage and religation activities of human topoisomerase I.
Biochem J
; 425(3): 531-9, 2010 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19883377
16.
Evidence of the crucial role of the linker domain on the catalytic activity of human topoisomerase I by experimental and simulative characterization of the Lys681Ala mutant.
Nucleic Acids Res
; 37(20): 6849-58, 2009 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-19767617
17.
Simple and Fast DNA Based Sensor System for Screening of Small-Molecule Compounds Targeting Eukaryotic Topoisomerase 1.
Pharmaceutics
; 13(8)2021 Aug 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-34452216
18.
Synthesis of novel hybrid quinolino[4,3-b][1,5]naphthyridines and quinolino[4,3-b][1,5]naphthyridin-6(5H)-one derivatives and biological evaluation as topoisomerase I inhibitors and antiproliferatives.
Eur J Med Chem
; 195: 112292, 2020 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32279049
19.
Swapping of The N-Terminal Domain of Human Topoisomerase 1B with the Corresponding Plasmodium Falciparum Counterpart Strongly Impairs Enzyme Activity.
Rep Biochem Mol Biol
; 8(4): 366-375, 2020 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-32582794
20.
Different Camptothecin Sensitivities in Subpopulations of Colon Cancer Cells Correlate with Expression of Different Phospho-Isoforms of Topoisomerase I with Different Activities.
Cancers (Basel)
; 12(5)2020 May 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-32423158