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1.
Modeling of Blood-Brain Barrier (BBB) Dysfunction and Immune Cell Migration Using Human BBB-on-a-Chip for Drug Discovery Research.
Int J Mol Sci
; 25(12)2024 Jun 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-38928202
2.
Reconstituted Human Organ Models as a Translational Tool for Human Organ Response: Definition, Expectations, Cases, and Strategies for Implementation in Drug Discovery and Development.
Biol Pharm Bull
; 43(3): 375-383, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32115499
3.
Optimized methods for targeted peptide-based quantification of human uridine 5'-diphosphate-glucuronosyltransferases in biological specimens using liquid chromatography-tandem mass spectrometry.
Drug Metab Dispos
; 42(5): 885-9, 2014 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-24595681
4.
Species differences in intestinal glucuronidation activities between humans, rats, dogs and monkeys.
Xenobiotica
; 44(3): 205-16, 2014 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-23962030
5.
Quantitative prediction of human intestinal glucuronidation effects on intestinal availability of UDP-glucuronosyltransferase substrates using in vitro data.
Drug Metab Dispos
; 40(9): 1771-7, 2012 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-22685216
6.
Modelling and Prevention of Acute Kidney Injury through Ischemia and Reperfusion in a Combined Human Renal Proximal Tubule/Blood Vessel-on-a-Chip.
Kidney360
; 3(2): 217-231, 2022 02 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-35373131
7.
Perspectives on the evaluation and adoption of complex in vitro models in drug development: Workshop with the FDA and the pharmaceutical industry (IQ MPS Affiliate).
ALTEX
; 39(2): 297314, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35064273
8.
Recent Progress in Hepatocyte Culture Models and Their Application to the Assessment of Drug Metabolism, Transport, and Toxicity in Drug Discovery: The Value of Tissue Engineering for the Successful Development of a Microphysiological System.
J Pharm Sci
; 106(9): 2302-2311, 2017 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-28533121
9.
Newly developed rat brain pericyte cell line, TR-PCT1, responds to transforming growth factor-beta1 and beta-glycerophosphate.
Eur J Cell Biol
; 81(3): 145-52, 2002 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-11998866
10.
Glucuronidation and subsequent biliary excretion of mycophenolic acid in rat sandwich-cultured hepatocytes.
Drug Metab Pharmacokinet
; 29(2): 129-34, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-24025987
11.
Species differences in sinusoidal and canalicular efflux transport of mycophenolic acid 7-O-glucuronide in sandwich-cultured hepatocytes.
Pharmacol Res Perspect
; 2(2): e00035, 2014 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-25505584
12.
HDAC inhibitors restore the capacity of aged mice to respond to haloperidol through modulation of histone acetylation.
Neuropsychopharmacology
; 39(6): 1469-78, 2014 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-24366052
13.
Quantitative prediction of intestinal glucuronidation of drugs in rats using in vitro metabolic clearance data.
Drug Metab Pharmacokinet
; 27(2): 171-80, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-21970858
14.
The l-isomer-selective transport of aspartic acid is mediated by ASCT2 at the blood-brain barrier.
J Neurochem
; 87(4): 891-901, 2003 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-14622120
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