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1.
A review on AI Safety in highly automated driving.
Front Artif Intell
; 5: 952773, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-36262462
2.
Novel potent inhibitors of the histone demethylase KDM1A (LSD1), orally active in a murine promyelocitic leukemia model.
Future Med Chem
; 9(11): 1161-1174, 2017 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28722470
3.
Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 2: Structure-Based Drug Design and Structure-Activity Relationship.
J Med Chem
; 60(5): 1693-1715, 2017 03 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-28186757
4.
Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 1: High-Throughput Screening and Preliminary Exploration.
J Med Chem
; 60(5): 1673-1692, 2017 03 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-28186755
5.
Compounds and methods for inhibiting histone demethylases: a patent evaluation of US20160102096A1.
Expert Opin Ther Pat
; 26(12): 1367-1370, 2016 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-27730846
6.
Discovery of a Novel Inhibitor of Histone Lysine-Specific Demethylase 1A (KDM1A/LSD1) as Orally Active Antitumor Agent.
J Med Chem
; 59(4): 1501-17, 2016 Feb 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-26702542
7.
Synthesis, biological characterization and molecular modeling insights of spirochromanes as potent HDAC inhibitors.
Eur J Med Chem
; 108: 53-67, 2016 Jan 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-26629860
8.
Structural, Spectroscopic, Thermodynamic and Kinetic Properties of Copper(II) Complexes with Tripodal Tetraamines.
Inorg Chem
; 37(16): 4022-4029, 1998 Aug 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-11670519
9.
Towards selective inhibition of histone deacetylase isoforms: what has been achieved, where we are and what will be next.
ChemMedChem
; 9(3): 523-6, 2014 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-24730063
10.
Synthesis, biological activity and mechanistic insights of 1-substituted cyclopropylamine derivatives: a novel class of irreversible inhibitors of histone demethylase KDM1A.
Eur J Med Chem
; 86: 352-63, 2014 Oct 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-25173853
11.
Cinnamic anilides as new mitochondrial permeability transition pore inhibitors endowed with ischemia-reperfusion injury protective effect in vivo.
J Med Chem
; 57(12): 5333-47, 2014 Jun 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-24918261
12.
Synthesis and biological characterization of spiro[2H-(1,3)-benzoxazine-2,4'-piperidine] based histone deacetylase inhibitors.
Eur J Med Chem
; 64: 273-84, 2013 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-23644210
13.
Current trends in the development of histone deacetylase inhibitors: a review of recent patent applications.
Pharm Pat Anal
; 1(1): 75-90, 2012 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-24236715
14.
Spiro[chromane-2,4'-piperidine]-based histone deacetylase inhibitors with improved in vivo activity.
ChemMedChem
; 7(4): 709-21, 2012 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-22354629
15.
Next generation histone deacetylase inhibitors: the answer to the search for optimized epigenetic therapies?
Expert Opin Drug Discov
; 6(4): 393-404, 2011 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-22646017
16.
Discovery, synthesis, and pharmacological evaluation of spiropiperidine hydroxamic acid based derivatives as structurally novel histone deacetylase (HDAC) inhibitors.
J Med Chem
; 54(8): 3051-64, 2011 Apr 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-21417419
17.
Synthesis and biological characterization of amidopropenyl hydroxamates as HDAC inhibitors.
ChemMedChem
; 5(8): 1359-72, 2010 Aug 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-20572281
18.
Synthesis and biological evaluation of N-hydroxyphenylacrylamides and N-hydroxypyridin-2-ylacrylamides as novel histone deacetylase inhibitors.
J Med Chem
; 53(2): 822-39, 2010 Jan 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-20017493
19.
A new approach to phosphoserine and phosphothreonine analysis in peptides and proteins: chemical modification, enrichment via solid-phase reversible binding, and analysis by mass spectrometry.
Anal Bioanal Chem
; 376(3): 366-73, 2003 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-12734628
20.
Inhibitor affinity chromatography: profiling the specific reactivity of the proteome with immobilized molecules.
Proteomics
; 3(7): 1287-98, 2003 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-12872229