Detalles de la búsqueda
1.
The dual GCGR/GLP-1R agonist survodutide: Biomarkers and pharmacological profiling for clinical candidate selection.
Diabetes Obes Metab
; 26(6): 2368-2378, 2024 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-38560764
2.
BI-Y, an Neuropilin-1 Antagonist, Enhances Revascularization and Prevents Vascular Endothelial Growth Factor-A Induced Retinal Hyperpermeability in Rodent Models of Retinopathies.
J Pharmacol Exp Ther
; 385(3): 214-221, 2023 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-36997325
3.
Deep Learning-Based Detection of Endothelial Tip Cells in the Oxygen-Induced Retinopathy Model.
Toxicol Pathol
; 49(4): 862-871, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33896293
4.
Design, synthesis and evaluation of MCH receptor 1 antagonists--Part III: Discovery of pre-clinical development candidate BI 186908.
Bioorg Med Chem Lett
; 25(16): 3275-80, 2015 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26105194
5.
Design, synthesis and evaluation of MCH receptor 1 antagonists--Part II: Optimization of pyridazines toward reduced phospholipidosis and hERG inhibition.
Bioorg Med Chem Lett
; 25(16): 3270-4, 2015 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26077492
6.
Collection of triatomines from sylvatic habitats by a Trypanosoma cruzi-infected scent detection dog in Texas, USA.
PLoS Negl Trop Dis
; 17(3): e0010813, 2023 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36940217
7.
Efficacy of an Anti-Semaphorin 3A Neutralizing Antibody in a Male Experimental Retinal Vein Occlusion Mouse Model.
Invest Ophthalmol Vis Sci
; 63(8): 14, 2022 07 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-35822950
8.
Sema3A Antibody BI-X Prevents Cell Permeability and Cytoskeletal Collapse in HRMECs and Increases Tip Cell Density in Mouse Oxygen-Induced Retinopathy.
Transl Vis Sci Technol
; 11(6): 17, 2022 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35727188
9.
BI 456906: Discovery and preclinical pharmacology of a novel GCGR/GLP-1R dual agonist with robust anti-obesity efficacy.
Mol Metab
; 66: 101633, 2022 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-36356832
10.
Deaths Among U.S. Air Force Basic Military Trainees, 2008-2020.
Mil Med
; 2022 Jan 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-35043203
11.
Retrospective case series of five nontraumatic deaths among U.S. Air Force basic military trainees (1997-2007).
Mil Med
; 176(8): 938-43, 2011 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-21882786
12.
Outcomes of Embedded Athletic Training Services Within United States Air Force Basic Military Training.
J Athl Train
; 56(2): 134-140, 2021 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33370444
13.
Can the detection dog alert on COVID-19 positive persons by sniffing axillary sweat samples? A proof-of-concept study.
PLoS One
; 15(12): e0243122, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-33301539
14.
Chronic treatment with the dipeptidyl peptidase-4 inhibitor BI 1356 [(R)-8-(3-amino-piperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydro-purine-2,6-dione] increases basal glucagon-like peptide-1 and improves glycemic control in diabetic rodent models.
J Pharmacol Exp Ther
; 328(2): 556-63, 2009 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-18971371
15.
Acetyl-CoA carboxylases 1 and 2 show distinct expression patterns in rats and humans and alterations in obesity and diabetes.
Diabetes Metab Res Rev
; 25(6): 577-86, 2009 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-19618481
16.
Article commentary on 'Microdosimetric and radiobiological effects of gold nanoparticles at therapeutic radiation energies' [T.M. Gray et al., IJRB 2023, 99(2), 308-317].
Int J Radiat Biol
; 100(1): 7-17, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-37549053
17.
(R)-8-(3-amino-piperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydro-purine-2,6-dione (BI 1356), a novel xanthine-based dipeptidyl peptidase 4 inhibitor, has a superior potency and longer duration of action compared with other dipeptidyl peptidase-4 inhibitors.
J Pharmacol Exp Ther
; 325(1): 175-82, 2008 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-18223196
18.
3,5-Dihydro-imidazo[4,5-d]pyridazin-4-ones: a class of potent DPP-4 inhibitors.
Bioorg Med Chem Lett
; 18(11): 3158-62, 2008 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18485703
19.
8-(3-(R)-aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydropurine-2,6-dione (BI 1356), a highly potent, selective, long-acting, and orally bioavailable DPP-4 inhibitor for the treatment of type 2 diabetes.
J Med Chem
; 50(26): 6450-3, 2007 Dec 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-18052023
20.
An RNA-Seq atlas of gene expression in mouse and rat normal tissues.
Sci Data
; 4: 170185, 2017 12 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-29231921