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7-(1,1-Dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine: a functionally selective gamma-aminobutyric acid(A) (GABA(A)) alpha2/alpha3-subtype selective agonist that exhibits potent anxiolytic activity but is not sedating in animal models.
J Med Chem
; 48(23): 7089-92, 2005 Nov 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-16279764
2.
3-Heteroaryl-2-pyridones: benzodiazepine site ligands with functional delectivity for alpha 2/alpha 3-subtypes of human GABA(A) receptor-ion channels.
J Med Chem
; 45(9): 1887-900, 2002 Apr 25.
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en Inglés
| MEDLINE | ID: mdl-11960500
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