Búsqueda | Biblioteca Virtual en Salud

1.

Antileukemia activity of the novel peptidic CXCR4 antagonist LY2510924 as monotherapy and in combination with chemotherapy.

Cho, Byung-Sik; Zeng, Zhihong; Mu, Hong; Wang, Zhiqiang; Konoplev, Sergej; McQueen, Teresa; Protopopova, Marina; Cortes, Jorge; Marszalek, Joseph R; Peng, Sheng-Bin; Ma, Wencai; Davis, R Eric; Thornton, Donald E; Andreeff, Michael; Konopleva, Marina.

Blood ; 126(2): 222-32, 2015 Jul 09.

Artículo en Inglés | MEDLINE | ID: mdl-26031918

2.

Phase I study of enzastaurin and bevacizumab in patients with advanced cancer: safety, efficacy and pharmacokinetics.

Nwankwo, Nwabundo; Zhang, Zhe; Wang, Ting; Collins, Connie; Resta, Lee; Ermisch, Sabine; Day, Jeannette; Decker, Rodney; Kornberg, Lori; Nicol, Steven; Thornton, Donald; Armstrong, Deborah K; Carducci, Michael A.

Invest New Drugs ; 31(3): 653-60, 2013 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-22766773

3.

A phase I trial of enzastaurin in patients with recurrent gliomas.

Kreisl, Teri N; Kim, Lyndon; Moore, Kraig; Duic, Paul; Kotliarova, Svetlana; Walling, Jennifer; Musib, Luna; Thornton, Donald; Albert, Paul S; Fine, Howard A.

Clin Cancer Res ; 15(10): 3617-23, 2009 May 15.

Artículo en Inglés | MEDLINE | ID: mdl-19417015

4.

Development and validation of a drug activity biomarker that shows target inhibition in cancer patients receiving enzastaurin, a novel protein kinase C-beta inhibitor.

Green, Lisa J; Marder, Philip; Ray, Chad; Cook, Carolyn A; Jaken, Susan; Musib, Luna C; Herbst, Roy S; Carducci, Michael; Britten, Carolyn D; Basche, Michele; Eckhardt, S Gail; Thornton, Donald.

Clin Cancer Res ; 12(11 Pt 1): 3408-15, 2006 Jun 01.

Artículo en Inglés | MEDLINE | ID: mdl-16740765

5.

The protein kinase Cbeta-selective inhibitor, Enzastaurin (LY317615.HCl), suppresses signaling through the AKT pathway, induces apoptosis, and suppresses growth of human colon cancer and glioblastoma xenografts.

Graff, Jeremy R; McNulty, Ann M; Hanna, Kimberly Ross; Konicek, Bruce W; Lynch, Rebecca L; Bailey, Spring N; Banks, Crystal; Capen, Andrew; Goode, Robin; Lewis, Jason E; Sams, Lillian; Huss, Karen L; Campbell, Robert M; Iversen, Philip W; Neubauer, Blake Lee; Brown, Thomas J; Musib, Luna; Geeganage, Sandaruwan; Thornton, Donald.

Cancer Res ; 65(16): 7462-9, 2005 Aug 15.

Artículo en Inglés | MEDLINE | ID: mdl-16103100

6.

A Phase 1 Study of LY2874455, an Oral Selective pan-FGFR Inhibitor, in Patients with Advanced Cancer.

Michael, Michael; Bang, Yung-Jue; Park, Young Suk; Kang, Yoon-Koo; Kim, Tae Min; Hamid, Oday; Thornton, Donald; Tate, Sonya C; Raddad, Eyas; Tie, Jeanne.

Target Oncol ; 12(4): 463-474, 2017 08.

Artículo en Inglés | MEDLINE | ID: mdl-28589492

7.

Phase I trial of the cryptophycin analogue LY355703 administered as an intravenous infusion on a day 1 and 8 schedule every 21 days.

Stevenson, James P; Sun, Weijing; Gallagher, Maryann; Johnson, Robert; Vaughn, David; Schuchter, Lynn; Algazy, Kenneth; Hahn, Stephen; Enas, Nathan; Ellis, Diane; Thornton, Donald; O'Dwyer, Peter J.

Clin Cancer Res ; 8(8): 2524-9, 2002 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-12171879

8.

Phase 2 study of cryptophycin 52 (LY355703) in patients previously treated with platinum based chemotherapy for advanced non-small cell lung cancer.

Edelman, Martin J; Gandara, David R; Hausner, Petr; Israel, Valerie; Thornton, Donald; DeSanto, Jennifer; Doyle, L Austin.

Lung Cancer ; 39(2): 197-9, 2003 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-12581573

9.

A phase I trial of LY2510924, a CXCR4 peptide antagonist, in patients with advanced cancer.

Galsky, Matthew D; Vogelzang, Nicholas J; Conkling, Paul; Raddad, Eyas; Polzer, John; Roberson, Stephanie; Stille, John R; Saleh, Mansoor; Thornton, Donald.

Clin Cancer Res ; 20(13): 3581-8, 2014 Jul 01.

Artículo en Inglés | MEDLINE | ID: mdl-24727324

10.

Phase II and pharmacogenomics study of enzastaurin plus temozolomide during and following radiation therapy in patients with newly diagnosed glioblastoma multiforme and gliosarcoma.

Butowski, Nicholas; Chang, Susan M; Lamborn, Kathleen R; Polley, Mei-Yin; Pieper, Russell; Costello, Joseph F; Vandenberg, Scott; Parvataneni, Rupa; Nicole, Angelina; Sneed, Patricia K; Clarke, Jennifer; Hsieh, Emily; Costa, Bruno M; Reis, Rui M; Hristova-Kazmierski, Maria; Nicol, Steven J; Thornton, Donald E; Prados, Michael D.

Neuro Oncol ; 13(12): 1331-8, 2011 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-21896554

11.

A phase I/II trial of enzastaurin in patients with recurrent high-grade gliomas.

Kreisl, Teri N; Kotliarova, Svetlana; Butman, John A; Albert, Paul S; Kim, Lyndon; Musib, Luna; Thornton, Donald; Fine, Howard A.

Neuro Oncol ; 12(2): 181-9, 2010 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-20150385

12.

Phase III study of enzastaurin compared with lomustine in the treatment of recurrent intracranial glioblastoma.

Wick, Wolfgang; Puduvalli, Vinay K; Chamberlain, Marc C; van den Bent, Martin J; Carpentier, Antoine F; Cher, Lawrence M; Mason, Warren; Weller, Michael; Hong, Shengyan; Musib, Luna; Liepa, Astra M; Thornton, Donald E; Fine, Howard A.

J Clin Oncol ; 28(7): 1168-74, 2010 Mar 01.

Artículo en Inglés | MEDLINE | ID: mdl-20124186

13.

Enzastaurin plus temozolomide with radiation therapy in glioblastoma multiforme: a phase I study.

Butowski, Nicholas; Chang, Susan M; Lamborn, Kathleen R; Polley, Mei Yin; Parvataneni, R; Hristova-Kazmierski, Maria; Musib, Luna; Nicol, Steven J; Thornton, Donald E; Prados, Michael D.

Neuro Oncol ; 12(6): 608-13, 2010 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-20156802

14.

A liver transplant patient.

Thornton, Donald.

Hepatobiliary Pancreat Dis Int ; 2(4): 626; author reply 626-7, 2003 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-14979297

15.

In Vivo Measurements of Tumor Metabolism and Growth after Administration of Enzastaurin Using Small Animal FDG Positron Emission Tomography.

Pollok, Karen E; Lahn, Michael; Enas, Nathan; McNulty, Ann; Graff, Jeremy; Cai, Shanbao; Hartwell, Jennifer R; Ernstberger, Aaron; Thornton, Donald; Brail, Les; Hutchins, Gary.

J Oncol ; 2009: 596560, 2009.

Artículo en Inglés | MEDLINE | ID: mdl-19503801

16.

A phase I safety, tolerability, and pharmacokinetic study of enzastaurin combined with capecitabine in patients with advanced solid tumors.

Camidge, D Ross; Gail Eckhardt, S; Gore, Lia; O'Bryant, Cindy L; Leong, Stephen; Basche, Michelle; Holden, Scott N; Musib, Luna; Baldwin, John; Darstein, Christelle; Thornton, Donald; Finn, Richard S; Britten, Carolyn D.

Anticancer Drugs ; 19(1): 77-84, 2008 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-18043132

17.

Utilization and cost of health care services associated with primary malignant brain tumors in the United States.

Kutikova, Lucie; Bowman, Lee; Chang, Stella; Long, Stacey R; Thornton, Donald E; Crown, William H.

J Neurooncol ; 81(1): 61-5, 2007 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-16773215

18.

Retrospective analysis of protein kinase C-beta (PKC-beta) expression in lymphoid malignancies and its association with survival in diffuse large B-cell lymphomas.

Li, Shuyu; Phong, Mark; Lahn, Michael; Brail, Leslie; Sutton, Susan; Lin, Boris K; Thornton, Donald; Liao, Birong.

Biol Direct ; 2: 8, 2007 Feb 21.

Artículo en Inglés | MEDLINE | ID: mdl-17313671

19.

Phase II study of enzastaurin, a protein kinase C beta inhibitor, in patients with relapsed or refractory diffuse large B-cell lymphoma.

Robertson, Michael J; Kahl, Brad S; Vose, Julie M; de Vos, Sven; Laughlin, Mary; Flynn, Patrick J; Rowland, Kendrith; Cruz, Jose C; Goldberg, Stuart L; Musib, Luna; Darstein, Christelle; Enas, Nathan; Kutok, Jeffery L; Aster, Jon C; Neuberg, Donna; Savage, Kerry J; LaCasce, Ann; Thornton, Donald; Slapak, Christopher A; Shipp, Margaret A.

J Clin Oncol ; 25(13): 1741-6, 2007 May 01.

Artículo en Inglés | MEDLINE | ID: mdl-17389337

20.

Phase I dose escalation and pharmacokinetic study of enzastaurin, an oral protein kinase C beta inhibitor, in patients with advanced cancer.

Carducci, Michael A; Musib, Luna; Kies, Merrill S; Pili, Roberto; Truong, Mylene; Brahmer, Julie R; Cole, Patricia; Sullivan, Rana; Riddle, Jeanne; Schmidt, Jill; Enas, Nathan; Sinha, Vikram; Thornton, Donald E; Herbst, Roy S.

J Clin Oncol ; 24(25): 4092-9, 2006 Sep 01.

Artículo en Inglés | MEDLINE | ID: mdl-16943527

Biblioteca Virtual en Salud

Hipertensión

Su selección (0)

Formato de exportación:

Exportar: