Detalles de la búsqueda
1.
Discovery of 5-((1H-indazol-3-yl) methylene)-2-thioxoimidazolidin-4-one derivatives as a new class of AHR agonists with anti-psoriasis activity in a mouse model.
Bioorg Med Chem Lett
; 92: 129383, 2023 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37348572
2.
Tertiary lymphoid structure patterns predicted anti-PD1 therapeutic responses in gastric cancer.
Chin J Cancer Res
; 34(4): 365-382, 2022 Aug 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-36199531
3.
Discovery of 5-(4-methylpiperazin-1-yl)-2-nitroaniline derivatives as a new class of SIRT6 inhibitors.
Bioorg Med Chem Lett
; 30(16): 127215, 2020 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32631504
4.
Preclinical pharmacodynamic evaluation of a new Src/FOSL1 inhibitor, LY-1816, in pancreatic ductal adenocarcinoma.
Cancer Sci
; 110(4): 1408-1419, 2019 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-30618127
5.
From Hit to Lead: Structure-Based Optimization of Novel Selective Inhibitors of Receptor-Interacting Protein Kinase 1 (RIPK1) for the Treatment of Inflammatory Diseases.
J Med Chem
; 67(1): 754-773, 2024 Jan 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-38159286
6.
Study of the Effect of Intestinal Microbes on Obesity: A Bibliometric Analysis.
Nutrients
; 15(14)2023 Jul 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-37513673
7.
Intraoperative Pathological Evaluation of Suspicious Peritoneal Nodules for Surgical Decision-making in Gastric Cancer.
J Gastrointest Surg
; 27(8): 1545-1559, 2023 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37059962
8.
Association of systemic inflammatory markers and tertiary lymphoid structure with pathological complete response in gastric cancer patients receiving preoperative treatment: a retrospective cohort study.
Int J Surg
; 109(12): 4151-4161, 2023 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-38259000
9.
Single-cell RNA sequencing reveals the lineage of malignant epithelial cells and upregulation of TAGLN2 promotes peritoneal metastasis in gastric cancer.
Clin Transl Oncol
; 25(12): 3405-3419, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37247132
10.
A combination of eye-gaze and head-gaze interactions improves efficiency and user experience in an object positioning task in virtual environments.
Appl Ergon
; 103: 103785, 2022 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-35490546
11.
Identification of triazolopyridine derivatives as a new class of AhR agonists and evaluation of anti-psoriasis effect in a mouse model.
Eur J Med Chem
; 231: 114122, 2022 Mar 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35123295
12.
Identification of metabolism-related genes for predicting peritoneal metastasis in patients with gastric cancer.
BMC Genom Data
; 23(1): 84, 2022 Dec 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-36503378
13.
Discovery of 3,4-Dihydrobenzo[f][1,4]oxazepin-5(2H)-one Derivatives as a New Class of Selective TNIK Inhibitors and Evaluation of Their Anti-Colorectal Cancer Effects.
J Med Chem
; 65(3): 1786-1807, 2022 02 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34985886
14.
Non-classical ferroptosis inhibition by a small molecule targeting PHB2.
Nat Commun
; 13(1): 7473, 2022 12 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36463308
15.
Generative deep learning enables the discovery of a potent and selective RIPK1 inhibitor.
Nat Commun
; 13(1): 6891, 2022 11 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-36371441
16.
Structural Optimization and Structure-Activity Relationship Studies of 6,6-Dimethyl-4-(phenylamino)-6H-pyrimido[5,4-b][1,4]oxazin-7(8H)-one Derivatives as A New Class of Potent Inhibitors of Pan-Trk and Their Drug-Resistant Mutants.
J Med Chem
; 65(3): 2035-2058, 2022 02 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-35080890
17.
An orally available Mpro inhibitor is effective against wild-type SARS-CoV-2 and variants including Omicron.
Nat Microbiol
; 7(5): 716-725, 2022 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35477751
18.
Small molecules in targeted cancer therapy: advances, challenges, and future perspectives.
Signal Transduct Target Ther
; 6(1): 201, 2021 05 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-34054126
19.
Demethylation of the SFRP4 Promoter Drives Gastric Cancer Progression via the Wnt Pathway.
Mol Cancer Res
; 19(9): 1454-1464, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34016745
20.
Discovery and structure-activity relationship studies of 1-aryl-1H-naphtho[2,3-d][1,2,3]triazole-4,9-dione derivatives as potent dual inhibitors of indoleamine 2,3-dioxygenase 1 (IDO1) and trytophan 2,3-dioxygenase (TDO).
Eur J Med Chem
; 207: 112703, 2020 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32871341