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1.
Discovery and Optimization of 5-Hydroxy-Diclofenac toward a New Class of Ligands with Nanomolar Affinity for the CaMKIIα Hub Domain.
J Med Chem
; 65(9): 6656-6676, 2022 05 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-35500061
2.
Exploring the NCS-382 Scaffold for CaMKIIα Modulation: Synthesis, Biochemical Pharmacology, and Biophysical Characterization of Ph-HTBA as a Novel High-Affinity Brain-Penetrant Stabilizer of the CaMKIIα Hub Domain.
J Med Chem
; 65(22): 15066-15084, 2022 11 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-36346645
3.
Discovery of 2-(Imidazo[1,2- b]pyridazin-2-yl)acetic Acid as a New Class of Ligands Selective for the γ-Hydroxybutyric Acid (GHB) High-Affinity Binding Sites.
J Med Chem
; 62(5): 2798-2813, 2019 03 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-30763084
4.
Molecular Hybridization of Potent and Selective γ-Hydroxybutyric Acid (GHB) Ligands: Design, Synthesis, Binding Studies, and Molecular Modeling of Novel 3-Hydroxycyclopent-1-enecarboxylic Acid (HOCPCA) and trans-γ-Hydroxycrotonic Acid (T-HCA) Analogs.
J Med Chem
; 60(21): 9022-9039, 2017 11 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-29028338
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