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1.
An anchor-tether 'hindered' HCN1 inhibitor is antihyperalgesic in a rat spared nerve injury neuropathic pain model.
Br J Anaesth
; 131(4): 745-763, 2023 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-37567808
2.
HCN1 channels as targets for anesthetic and nonanesthetic propofol analogs in the amelioration of mechanical and thermal hyperalgesia in a mouse model of neuropathic pain.
J Pharmacol Exp Ther
; 345(3): 363-73, 2013 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-23549867
3.
Probucol is anti-hyperalgesic in a mouse peripheral nerve injury model of neuropathic pain.
Neurobiol Pain
; 14: 100141, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-38099280
4.
PIP2-mediated HCN3 channel gating is crucial for rhythmic burst firing in thalamic intergeniculate leaflet neurons.
J Neurosci
; 31(28): 10412-23, 2011 Jul 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-21753018
5.
Voltage-dependent opening of HCN channels: Facilitation or inhibition by the phytoestrogen, genistein, is determined by the activation status of the cyclic nucleotide gating ring.
Biochim Biophys Acta
; 1788(9): 1939-49, 2009 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-19524546
6.
Probing S4 and S5 segment proximity in mammalian hyperpolarization-activated HCN channels by disulfide bridging and Cd2+ coordination.
Pflugers Arch
; 458(2): 259-72, 2009 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-19034494
7.
Alkylphenol inverse agonists of HCN1 gating: H-bond propensity, ring saturation and adduct geometry differentially determine efficacy and potency.
Biochem Pharmacol
; 163: 493-508, 2019 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-30768926
8.
HCN pacemaker channel activation is controlled by acidic lipids downstream of diacylglycerol kinase and phospholipase A2.
J Neurosci
; 27(11): 2802-14, 2007 Mar 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-17360902
9.
HCN and K2P Channels in Anesthetic Mechanisms Research.
Methods Enzymol
; 602: 391-416, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29588040
10.
Voltage-Gated Ion Channels in the PNS: Novel Therapies for Neuropathic Pain?
Trends Pharmacol Sci
; 37(7): 522-542, 2016 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-27233519
11.
cAMP control of HCN2 channel Mg2+ block reveals loose coupling between the cyclic nucleotide-gating ring and the pore.
PLoS One
; 9(7): e101236, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-24983358
12.
Ion binding in the open HCN pacemaker channel pore: fast mechanisms to shape "slow" channels.
J Gen Physiol
; 131(3): 227-43, 2008 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-18270171
13.
Propofol inhibits HCN1 pacemaker channels by selective association with the closed states of the membrane embedded channel core.
J Physiol
; 583(Pt 1): 37-56, 2007 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-17569731
14.
Impairment of hyperpolarization-activated, cyclic nucleotide-gated channel function by the intravenous general anesthetic propofol.
J Pharmacol Exp Ther
; 315(2): 517-25, 2005 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-16033909
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