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1.
Straightforward Access to a New Class of Dual DYRK1A/CLK1 Inhibitors Possessing a Simple Dihydroquinoline Core.
Molecules
; 28(1)2022 Dec 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-36615235
2.
Access to Highly Enantioenriched Donepezil-like 1,4-Dihydropyridines as Promising Anti-Alzheimer Prodrug Candidates via Enantioselective Tsuji Allylation and Organocatalytic Aza-Ene-Type Domino Reactions.
J Org Chem
; 83(17): 10231-10240, 2018 09 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30004228
3.
Palladium-Catalyzed Carbonylation of (Hetero)Aryl, Alkenyl and Allyl Halides by Means of N-Hydroxysuccinimidyl Formate as CO Surrogate.
J Org Chem
; 80(13): 6537-44, 2015 Jul 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-26098725
4.
Design, synthesis and preliminary biological evaluation of rivastigmine-INDY hybrids as multitarget ligands against Alzheimer's disease by targeting butyrylcholinesterase and DYRK1A/CLK1 kinases.
RSC Med Chem
; 15(3): 963-980, 2024 Mar 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-38516603
5.
(3-Chloro-phen-yl){2-eth-oxy-5-[(Z)-hydroxy(phen-yl)methyl-idene]cyclo-penta-1,3-dien-1-yl}methanone.
Acta Crystallogr Sect E Struct Rep Online
; 68(Pt 2): o310-1, 2012 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22346947
6.
Chemical Delivery System of MIBG to the Central Nervous System: Synthesis, 11C-Radiosynthesis, and in Vivo Evaluation.
ACS Med Chem Lett
; 10(3): 352-357, 2019 Mar 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-30891139
7.
Novel donepezil-like N-benzylpyridinium salt derivatives as AChE inhibitors and their corresponding dihydropyridine "bio-oxidizable" prodrugs: Synthesis, biological evaluation and structure-activity relationship.
Eur J Med Chem
; 145: 165-190, 2018 Feb 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-29324339
8.
Rational design of carbamate-based dual binding site and central AChE inhibitors by a "biooxidisable" prodrug approach: Synthesis, in vitro evaluation and docking studies.
Eur J Med Chem
; 155: 171-182, 2018 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29886321
9.
Delivering FLT to the Central Nervous System by Means of a Promising Targeting System: Synthesis, [11C]Radiosynthesis, and in Vivo Evaluation.
ACS Chem Neurosci
; 8(11): 2457-2467, 2017 11 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28787127
10.
Donepezil-Based Central Acetylcholinesterase Inhibitors by Means of a "Bio-Oxidizable" Prodrug Strategy: Design, Synthesis, and in Vitro Biological Evaluation.
J Med Chem
; 60(13): 5909-5926, 2017 07 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-28613859
11.
Dihydroquinoline Carbamate Derivatives as "Bio-oxidizable" Prodrugs for Brain Delivery of Acetylcholinesterase Inhibitors: [¹¹C] Radiosynthesis and Biological Evaluation.
ACS Chem Neurosci
; 6(5): 737-44, 2015 May 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-25695305
12.
New developments in redox chemical delivery systems by means of 1,4-dihydroquinoline-based targetor: application to galantamine delivery to the brain.
Eur J Med Chem
; 81: 218-26, 2014 Jun 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-24852273
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