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1.
High-Throughput Therapeutic Antibody Interference-Free High-Resolution Mass Spectrometry Assay for Monitoring M-Proteins in Multiple Myeloma.
Anal Chem
; 93(2): 834-842, 2021 01 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-33300779
2.
Cynomolgus Monkey as a Clinically Relevant Model to Study Transport Involving Renal Organic Cation Transporters: In Vitro and In Vivo Evaluation.
Drug Metab Dispos
; 44(2): 238-49, 2016 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-26608080
3.
Innovative use of LC-MS/MS for simultaneous quantitation of neutralizing antibody, residual drug, and human immunoglobulin G in immunogenicity assay development.
Anal Chem
; 86(5): 2673-80, 2014 Mar 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-24506335
4.
Fully validated LC-MS/MS assay for the simultaneous quantitation of coadministered therapeutic antibodies in cynomolgus monkey serum.
Anal Chem
; 85(20): 9859-67, 2013 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24024648
5.
Practical and efficient strategy for evaluating oral absolute bioavailability with an intravenous microdose of a stable isotopically-labeled drug using a selected reaction monitoring mass spectrometry assay.
Anal Chem
; 84(22): 10031-7, 2012 Nov 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-23106420
6.
Concerted application of LC-MS and ligand binding assays to better understand exposure of a large molecule drug.
Bioanalysis
; 10(16): 1261-1272, 2018 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29923414
7.
SKI-606, a Src/Abl inhibitor with in vivo activity in colon tumor xenograft models.
Cancer Res
; 65(12): 5358-64, 2005 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-15958584
8.
Overcoming interference with the detection of a stable isotopically labeled microtracer in the evaluation of beclabuvir absolute bioavailability using a concomitant microtracer approach.
J Pharm Biomed Anal
; 143: 9-16, 2017 Sep 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-28544885
9.
Singlicate Ligand Binding Assay Using an Automated Microfluidic System: a Clinical Case Study.
AAPS J
; 19(5): 1461-1468, 2017 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-28589510
10.
Development and characterization of a pre-treatment procedure to eliminate human monoclonal antibody therapeutic drug and matrix interference in cell-based functional neutralizing antibody assays.
J Immunol Methods
; 416: 94-104, 2015 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-25445325
11.
An exploratory universal LC-MS/MS assay for bioanalysis of hinge region-stabilized human IgG4 mAbs in clinical studies.
Bioanalysis
; 6(13): 1747-58, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-24661028
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